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XVIII<br />

Contents<br />

25 Absent End-Diastolic Velocity<br />

in the Umbilical Artery<br />

and Its Clinical Significance ......... 375<br />

Dev Maulik, Reinaldo Figueroa<br />

Incidence ....................... 376<br />

Technical Considerations ............. 376<br />

Absent End-Diastolic Velocity and Adverse<br />

Perinatal Outcome ................. 377<br />

Perinatal Mortality ............... 377<br />

Perinatal Morbidity ............... 377<br />

Maternal Hypertension and Absent End-<br />

Diastolic Velocity .................. 382<br />

Reappearance of End-Diastolic Velocity .. 382<br />

AREDVand Other Emergent Signs of Fetal<br />

Compromise ..................... 383<br />

Summary ....................... 384<br />

References .................... 384<br />

26 Doppler Velocimetry for Fetal Surveillance:<br />

Randomized Clinical Trials<br />

and Implications for Practice ........ 387<br />

Dev Maulik, Reinaldo Figueroa<br />

Doppler Randomized Trials: A Summary .. 387<br />

Doppler Randomized Trials: Cumulative<br />

Summary ....................... 392<br />

Population Characteristics .......... 392<br />

Objective and Primary Outcome ..... 393<br />

Doppler Sonographic Technique<br />

and Research Design ............. 393<br />

Management Protocol ............ 393<br />

Doppler Randomized Trials: Meta-Analysis 393<br />

Meta-Analysis: Brief Introduction ..... 393<br />

Doppler Meta-Analysis ............ 395<br />

Management of High-Risk Pregnancy: A<br />

Proposal Based on Clinical Trials ....... 398<br />

Conclusion ...................... 399<br />

References .................... 399<br />

27 Doppler Investigation<br />

of the Fetal Inferior Vena Cava ....... 403<br />

Yoshihide Chiba, Toru Kanzaki,<br />

Zeev Weiner<br />

Normal Blood Flow Pattern in Fetal IVC .. 403<br />

Doppler Evaluation of Preload Condition<br />

in the Fetal Vena Cava and the Umbilical<br />

Vein ........................... 404<br />

Preload Index .................. 404<br />

Blood Flow Change During Fetal<br />

Therapy ...................... 406<br />

Blood Flow Dynamics in Fetal Central<br />

Veins During Labor .............. 406<br />

IVC Blood Flow at an Early Stage<br />

of Pregnancy ................... 407<br />

Abnormal IVC Blood Flow Patterns<br />

with Fetal Arrhythmias .............. 407<br />

Blood Flow Pattern of Premature<br />

Contractions ................... 408<br />

Bradycardic Arrhythmia ........... 408<br />

Tachyarrhythmias ................ 408<br />

Determination of Fetal Therapy<br />

According to the Type of Tachycardia . 410<br />

IVC and Umbilical Vein Blood Flow Patterns<br />

in High-Risk Fetuses ................ 410<br />

References .................... 411<br />

28 Ductus Venosus .................. 413<br />

Torvid Kiserud<br />

Anatomy and Development .......... 413<br />

Physiological Background ............ 414<br />

Via Sinistra .................... 414<br />

Umbilical Liver Perfusion .......... 415<br />

Portal Watershed Area ............ 416<br />

Porto-Caval Pressure Gradient ....... 416<br />

Fetal Respiratory Force ............ 416<br />

Postnatal Physiology ............. 416<br />

Ultrasound Imaging and Insonation ..... 417<br />

Normal Ductus Venosus Blood Velocity .. 418<br />

Waveform Analysis: Indices ........... 419<br />

Interpretation of the Waveform ........ 420<br />

The Atrial Contraction Wave ........ 420<br />

Systolic Wave .................. 421<br />

Pitfalls ....................... 421<br />

Reproducibility ................. 422<br />

Agenesis of the Ductus Venosus ....... 423<br />

References ...................... 423<br />

29 Doppler Ultrasound Examination<br />

of the Fetal Coronary Circulation ..... 429<br />

Ahmet Alexander Baschat<br />

Introduction ..................... 429<br />

Embryology and Functional Anatomy<br />

of the Coronary Circulation ........... 429<br />

Ultrasound Examination Technique ..... 430<br />

Ultrasound Setup ................ 430<br />

Examination of Coronary Arteries .... 431<br />

Examination of the Coronary Sinus ... 432<br />

Clinical Applications in Fetuses<br />

with Normal Cardiac Anatomy ......... 436<br />

The ªHeart-Sparing Effectº in Fetal<br />

Growth Restriction ............... 436<br />

Fetal Anemia ................... 436<br />

Ductus Arteriosus Constriction ...... 437<br />

Other Fetal Conditions ............ 437

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