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a Chapter 4 Spectral Doppler Sonography: Waveform Analysis and Hemodynamic Interpretation 41<br />

Alternative Methods of Doppler Flowmetry<br />

Measured Instantaneous Velocity Profile<br />

Method ±The Multigated Doppler<br />

In this technique, the individual velocity components<br />

across the vascular lumen are measured using multigated<br />

pulse-wave Doppler. As in the previous technique,<br />

it is also necessary to measure the beam-vessel<br />

angle in order to transform the Doppler frequency<br />

shift information into velocity data. The summation<br />

of these velocity components constitutes the volumetric<br />

flow. An advanced implementation of this<br />

approach (Cardiosonix, Neoprobe Ltd, Dublin, Ohio,<br />

USA) has been reported in which two ultrasound<br />

beams set at a fixed known angle are used and numerous<br />

small (< 200 mm length) sample volumes at<br />

successive depths are collected and analyzed by fast<br />

Fourier transform in real time [10] (Fig. 4.7). The angle<br />

of insonation and the flow diameter are automatically<br />

computed allowing measurement of volumetric<br />

flow in real time. This technique is at present limited<br />

to assessing superficial vessels such as the carotid arteries<br />

and is not available for maternal or fetal applications.<br />

Vector Doppler ±Multiple Beam Insonation<br />

Doppler methods as described above measure the<br />

component of flow velocity parallel to the vascular<br />

axis but not the velocity components from the secondary<br />

flows resulting from vessel curvatures, bifurcations,<br />

and pulsatility. One of the techniques that attempts<br />

to resolve this limitation utilizes multiple<br />

transducers to measure multiple velocity vectors in a<br />

circulation and is also known as vector Doppler. Systems<br />

utilizing a single transmitter and two or more<br />

receivers to measure the various velocity vector components<br />

have been described [11, 12]. Experiments<br />

using a dual-beam vector Doppler system based on a<br />

modified linear array show that this system has low<br />

dependence on angle and similar reproducibility to<br />

that of single-beam systems [13]. These devices are<br />

not available yet for clinical use in obstetrics.<br />

Non-Doppler Flowmetry ± Time Domain<br />

Processing Velocity Measurement<br />

Time domain processing is an emerging field with a<br />

tremendous potential for offering a viable alternative<br />

to Doppler sonography. The basic implementations of<br />

time domain processing for measuring velocity and<br />

volume flow are briefly discussed below. Most of<br />

these still remain experimental in nature.<br />

Ultrasound B-Flow<br />

As the name implies, this innovative technology is<br />

based on B-mode ultrasound and allows imaging of<br />

blood flow. It utilizes digital ultrasound which allows<br />

encoding of the signals on transmission and decoding<br />

of the returning echoes into separate tissue and blood<br />

signals. As the echogenicity of blood is substantially<br />

lower than that of tissue, the returning signals are<br />

processed and equalized to enhance blood flow signals<br />

over those from the tissue. Whereas color Doppler<br />

duplex ultrasound imaging requires separate activation<br />

of the transducer elements for the Doppler<br />

Fig. 4.7. Multigated angle-independent Doppler flow measurement<br />

as implemented in a commercial system. Schematic<br />

representation of the FlowGuard technology. The<br />

ADBF technology uses 2 ultrasound beams (L1and L2)<br />

crossing the vessel lumen with a known angle (h) between<br />

them and allows the simultaneous acquisition of hundreds<br />

of small sample volumes (small dots) of less than 200 lm<br />

in depth (D) along L1 and L2. This in turn authorizes accurate<br />

determination of the flow velocity profile, vessel diameter,<br />

and isonation angle (h). (With permission from [10])<br />

Fig. 4.8. Ultrasound B flow imaging of blood flow in the<br />

umbilical vessels. The flow image is simultaneously derived<br />

along with B imaging and not superimposed. (With permission<br />

from General Electric Health Care System, Milwaukee,<br />

WI)

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