o_1977r8vv9vk1ts2ms0kd8pksa.pdf

244 E.R. Guzman et al.
Table 16.5. Uterine Doppler velocimetry screening studies
Study:
first author
Population Equipment No. Time of
screening
(weeks)
Outcome measure Sens
(%)
Spec
(%)
PPV
(%)
NPV
(%)
Prev
(%)
Arduini [81] High risk for PIH PD 60 18±20 PIH with or without proteinuria 63.6 84.2 70 80 36.6
PD 91 24 Proteinuric preeclampsia 66.7 ± 16.7 ± 9.7
Jacobson [82] High risk for preeclampsia
and IUGR
± ± ± ± ± IUGR 70.6 ± 33.3 ± 18.3
Campbell [40] Consecutive patients PD 126 16±20 PIH, IUGR, and fetal asphyxia a 68 69 42 87 25
± ± ± ± ± PIH 67 64 20 ± 12
Harrington [83] Unselected CWD, CD, PD 2,437 20 Proteinuric PIH 76 86 13 99 2.4
± ± ± ± 24 ± 76 96 35 99 ±
± ± ± ± 26 ± 74 97 44 99 ±
Valensise [84] Low risk, primiparous CD, PD 272 22 Total GH 74 97 76 97 9.9
± ± ± ± ± IUGR 66 95 53 97 7.7
± ± ± ± ± GH alone 50 92 23 97 4.4
± ± ± ± ± GH with proteinuria 88 93 30 99 3.3
± ± ± ± GH and IUGR 100 93 38 100 3.7
± ± ± ± ± Onset of GH
± ± ± ± ± 110 mmHg
90 mmHg
100 94 50 100 4.8
Bower [85] Unselected CWD, CD, PD 2,058 18±22 Preeclampsia 82 86.9 12 99.5 2.2
± ± ± ± ± PIH 15.7 85 7 93 6.5
± ± ± 2,026 24 Preeclampsia 78 96 28 99.5 1.8
± ± ± ± ± PIH 4.5 95 5.7 94 6.4
88
44
95
91
57
18
95
97
6.3
3.3
PIH, pregnancy-induced hypertension; IUGR, intrauterine growth restriction; SGA, small-for-gestational age; HTN, hypertension; IUD, intrauterine death; GH, gestational hypertension;
PD, pulsed Doppler; CWD, continuous-wave Doppler; CD, color Doppler; BP, blood pressure; Sens, sensitivity; Spec, specificity; PPV, positive predictive value; NPV,
negative predictive value; Prev, prevalence.
a Taken together to define outcome measures.