o_1977r8vv9vk1ts2ms0kd8pksa.pdf

a Chapter 24 Doppler Velocimetry for Fetal Surveillance: Adverse Perinatal Outcome and Fetal Hypoxia 369
Table 24.3. Association between fetal Doppler results and fetal blood gases
Study,
first author
No. of
patients
Patient risk
category
Cord blood
sampling
Doppler
assessment
Acid-base
parameters
Association
correlation
Soothill [19] 29 SGA Cordocentesis Aortic MVpH, PO 2 ,PCO 2 Present
Nicolaides [20] 59 SGA Cordocentesis UA AEDVpH, PO 2 Present
Ferrazzi [31] 14 High risk C/S UA PI pH, PCO 2 , Present
lactate
Tyrrell [22] 112 Unselected C/S UA AEDVpH, PO 2 Present
Bilardo [27] 51 SGA
Cordocentesis UA, aortic, pH, PO 2 Present
AGA
carotid PI,
RI, MV
Vintzileos [24] a 62 High risk C/S UA S/D pH Absent
Yoon [25] a 105 Unselected C/S UA PI pH, PO 2 , Present
PCO 2
Pardi [22] b 21 SGA Cordocentesis UA PI pH, PO 2 , Present
PCO 2 , lactate
Yoon [25] a 24 High risk Cordocentesis UA PI pH, PO 2 ,
PCO 2
Present
SGA, small for gestational age; AGA, appropriate for gestational age; C/S, cesarean section; UA, umbilical artery; AEDV, absent
end-diastolic velocity; MV, mean velocity; PI, pulsatility index; RI, resistance index; S/D, systolic/diastolic ratio.
a Studies compared the Doppler method with the biophysical profile.
b Study compared fetal heart rate monitoring with the Doppler method.
nous blood PO 2 , PCO 2 , pH, and plasma lactate were
measured in 29 fetuses with growth restriction (abdominal
circumference < 5th percentile for gestational
age). A duplex Doppler device was used to determine
the mean velocity of aortic blood flow, which demonstrated
significant negative correlations with the severity
of fetal hypoxia (r=±0.73, p