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474 D. Maulik<br />

technique, multigated Doppler sampling is performed<br />

on a single scan line, which is sampled 1,000 times a<br />

second, and the unidimensional tissue and color flow<br />

images are scrolled (usually from right to left on the<br />

video screen) and therefore displayed as a function of<br />

time. Because of the high sampling rate from a single<br />

line, the color M-mode technique provides a high<br />

Doppler sonographic sensitivity and temporal resolution<br />

and allows reliable timing of the flow with the<br />

events of the cardiac cycle. For these reasons, color<br />

M-mode sonographic technique is useful for fetal<br />

echocardiographic examination.<br />

Tissue Doppler Echocardiography<br />

Tissue Doppler sonography comprises processing and<br />

analyzing Doppler frequency shift generated by tissue<br />

movement. The physical and technical principles of<br />

tissue Doppler imaging of the heart are similar to<br />

those of Doppler sonography of blood flow with the<br />

exception of the approach to filtering. Doppler insonation<br />

of the heart generates signals from cardiac<br />

blood flow and myocardial movement. However, the<br />

Doppler signals generated by blood flow are of substantially<br />

lower amplitude and higher frequency than<br />

those from myocardial movement. In depicting flow,<br />

the high-pass filter system eliminates the high-amplitude<br />

and low-frequency myocardial Doppler signals<br />

so that only flow signals are displayed. In contrast,<br />

tissue Doppler echocardiography utilizes filtering that<br />

eliminates the low-amplitude high-frequency flow signals<br />

permitting tissue Doppler signals being displayed<br />

(Fig. 32.17). There are three types of tissue Doppler:<br />

pulse-wave tissue Doppler mode, color flow tissue<br />

Doppler mode, and color tissue Doppler M-mode.<br />

In the adult, tissue Doppler echocardiography has<br />

been used for assessing cardiac systolic and diastolic<br />

functions [20±22]. Such assessments can be performed<br />

by measuring myocardial velocity, myocardial<br />

velocity gradient, myocardial strain, and strain rate.<br />

Myocardial strain is its deformation during systole<br />

and diastole. Strain implies differential velocities in<br />

the cardiac wall and does not reflect overall movement<br />

of the heart including its translational motion<br />

within the thorax in relation to the other structures.<br />

Detailed reviews of these concepts may be found elsewhere<br />

[23].<br />

More recently the feasibility of tissue Doppler<br />

sonography for fetal cardiac assessment has been<br />

reported. Harada and associates measured motion<br />

Fig. 32.17. Tissue Doppler velocity waveforms from the right<br />

ventricular wall below the parietal insertion of the tricuspid<br />

valve. The sampling site is indicated by the horizontal arrow<br />

pointing to the Doppler sample volume (two horizontal lines).<br />

The diastolic and systolic velocity waveforms are indicated on<br />

the lower panel. A indicates arterial systole and E indicates<br />

end diastole. RA right atrium, LA left atrium, MV mitral valve,<br />

TV tricuspid valve, RV right ventricle, LV left ventricle

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