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a Chapter 21 Doppler Sonography in Pregnancies Complicated with Pregestational Diabetes Mellitus 333
Table 21.1. Diagnostic efficacy of umbilical arterial Doppler in diabetic pregnancy. PPV positive predictive value, NPV
negative predictive value, LR+ positive likelihood ratio, LR± negative likelihood ratio, FGR fetal growth restriction, FD fetal
distress, C/S cesarean section. (From [36])
Reference Outcome Prevalence Sensitivity Specificity PPV NPV LR+ LR± Accuracy
[10] Stillbirth 0.04 1 0.83 0.22 1 7.6 0 0.85
[11] FGR, FD 0.09 1 0.89 0.51 1 9.7 0 0.90
[12] FD 0.05 0.42 0.95 0.33 0.96 8.6 0.6 0.92
[15] C/S for FD 0.30 0.93 0.93 0.75 0.75 6.0 0.7 0.75
[16] Composite 0.23 0.32 0.92 0.57 0.81 4.2 0.7 0.78
[17] C/S for FD 0.27 0.61 0.75 0.48 0.84 2.5 0.5 0.71
Table 21.2. Umbilical arterial Doppler and maternal glycemic
control. S/D systolic to diastolic ratio, RI resistance index,
D the change, r correlation coefficient, NS not statistically
significant. (From [36])
Reference
Doppler
index
HbA1c D HbA1c Mean
blood
glucose
[10] S/D r =0.52,
p