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a Chapter 8 Biological Safety of Diagnostic Sonography 97<br />

Acoustic Characteristics<br />

Generation of heat in the insonated tissue depends<br />

essentially on the power and intensity of the ultrasound.<br />

Several acoustic features are involved in this<br />

process including the following:<br />

a. Acoustic power: The most relevant power parameter<br />

for thermal bioeffect is the spatial-peak temporal-average<br />

intensity (I SPTA ) which, as discussed<br />

in Chap. 2, is the highest time-averaged acoustic<br />

intensity at any point in the field. The output intensity<br />

varies with the application-specific default<br />

settings such as fetal, cardiac, or peripheral vascular<br />

investigations. The operator can supersede such<br />

regulations in choosing the mode. Most devices<br />

provide a control for altering the power output.<br />

Caution must be exercised in increasing the power<br />

indiscriminately as most obstetrical ultrasound examinations<br />

can be performed efficiently with the<br />

acoustic power set well below the regulatory limits.<br />

These issues will be discussed again.<br />

b. Focus: The I SPTA increases with focusing, which<br />

concentrates the power in a small area, causing<br />

higher intensities and increasing the potential for<br />

heating. Most diagnostic instruments employ a focused<br />

beam in order to enhance lateral resolution<br />

and directionality.<br />

c. Scanning vs stationary beam: The I SPTA intensity is<br />

affected by whether the ultrasound device utilizes<br />

a scanning or a stationary beam. In the scanning<br />

ultrasound modes, which include B-mode and color<br />

flow Doppler imaging, the moving beam temporally<br />

distributes the acoustic energy over a wide<br />

volume of tissue in the scanned area and thus<br />

minimizes the risk of tissue heating. In the stationary<br />

ultrasound modes, which include spectral<br />

Doppler and M-mode, the acoustic power is concentrated<br />

linearly along the static ultrasound beam<br />

axis, depositing acoustic energy in a significantly<br />

smaller volume of tissue for the duration of exposure.<br />

In this scenario, the highest elevation of temperature<br />

is encountered along the beam axis between<br />

the surface and proximal to the focal point,<br />

and its location is near the surface if the focal<br />

length is long and adjacent to the focal point if the<br />

focal length is short.<br />

d. Pulse repetition frequency (PRF): The higher the<br />

PRF, the greater the temporal average intensity.<br />

The PRF is under the user control, but can change<br />

automatically interactively with other controls such<br />

as the focal range. Increasing the focal range may<br />

automatically elevate the PRF. In spectral pulsed<br />

Doppler and color Doppler modes, the PRF is increased<br />

to eliminate aliasing which can result in<br />

increased I SPTA .<br />

e. Pulse length (also known as the pulse duration or<br />

burst length): This directly affects I SPTA . This is<br />

relevant for using the pulsed Doppler mode, as a<br />

larger Doppler sample volume will increase pulse<br />

duration which will increase the intensity. The<br />

pulse length is also greater in color flow Doppler<br />

than in B-mode imaging.<br />

f. Dwell time: This refers to the duration of ultrasound<br />

exposure. The longer the dwell time, the<br />

greater the thermal effect. During most fetal examinations<br />

the operator moves the transducer<br />

around, thereby reducing the duration of exposure<br />

in a given location. In using unscanned modes<br />

such as spectral Doppler interrogation of the middle<br />

cerebral artery, one needs to reduce the scan<br />

time deliberately because of the greater risk of<br />

thermal effect in this specific instance.<br />

g. Write zoom: In this function, where the image is<br />

magnified by rescanning a smaller area of interest<br />

in the image plane with more scan lines, the insonated<br />

tissue is exposed to a higher concentration<br />

of acoustic intensity. Moreover, using the write<br />

zoom box at a greater depth will lead to an even<br />

higher intensity as this requires a larger aperture<br />

involving more transducer elements emitting more<br />

power. This is especially applicable to the color<br />

flow Doppler color box function where a narrower<br />

and deeper color box will increase the intensity<br />

and the risk of temperature elevation. This risk is<br />

enhanced when color flow Doppler is used along<br />

with spectral pulsed Doppler in the duplex mode.<br />

h. Transducer frequency: Higher frequency ultrasound<br />

is more avidly absorbed by tissues, increasing<br />

the risk of heating. As higher frequency limits<br />

the depth of penetration, heating is restricted to<br />

the superficial tissues close to the transducer.<br />

Moreover, suboptimal depth resolution in this case<br />

may prompt the user to increase the power output,<br />

which may contribute to tissue heating.<br />

i. The nonlinearity of ultrasound propagation: In<br />

ultrasound pulses, especially the high amplitude<br />

waves, the compression in the wave propagates<br />

faster than the rarefaction, resulting in distortion<br />

in the waveform so that the peak of the wave follows<br />

the trough very closely. With the compression<br />

following the rarefaction very quickly, shock and<br />

harmonic components of higher frequencies are<br />

generated. This phenomenon is impeded in tissue<br />

with higher attenuation such as bone and is facilitated<br />

in tissue with lower attenuation such as amniotic<br />

fluid or even neural tissue. The higher frequency<br />

may lead to significant absorption of energy<br />

and conversion to heat. Although such thermal<br />

effects have not been demonstrated in the fetus,<br />

the potential exists, especially when ultrasound<br />

of higher amplitudes propagating through a

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