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580 I. Zalud<br />

cavity is ªcoldº with respect to blood flow, diagnosis<br />

of ectopic pregnancy is confirmed. It has been reported<br />

to increase the diagnostic sensitivity of sonography<br />

for ectopic pregnancy from 71% to 87% [32±<br />

34]. It also helps eliminate the problem of false positives,<br />

except in rare situations of ovarian pregnancy.<br />

Kurjak et al. have reported on the difference between<br />

the RI of the corpus luteum blood flow and<br />

peritrophoblastic flow of the ectopic pregnancy. The<br />

cutoff value for the RI of corpus luteum blood flow<br />

has been described to be 0.4 and the RI of peritrophoblastic<br />

blood flow below 0.4 [34]. Kirchler has described<br />

the use of Doppler blood flow in measuring<br />

the RI in tubal branches of the bilateral uterine arteries.<br />

The vessel with low-resistance flow indicates<br />

the side of the ectopic pregnancy [35].<br />

Endometrial color flow/image-directed Doppler<br />

imaging has also been reported to reduce the falsepositive<br />

TVS examinations which occur in 5%±10%<br />

of patients with high-risk findings. Ectopic pregnancy<br />

has no intrauterine trophoblastic activity, hence the<br />

presence of trophoblastic flow (arterial blood flow<br />

within the endometrium) lowers the risk of ectopic<br />

pregnancy whether an intrauterine gestational sac is<br />

present or not. However, care must be taken to ensure<br />

that arterial and not venous flow signals are obtained.<br />

The Doppler cursor should be completely within the<br />

endometrium to ensure that the signal is endometrial<br />

Fig. 39.15. High-velocity/low-impedance<br />

(RI=0.42) blood flow signals are<br />

obtained from the color-coded area<br />

and represent active, invasive trophoblast<br />

Fig. 39.16. Blood flow signals isolated<br />

from ipsilateral corpus luteum demonstrate<br />

a moderate to high resistance index<br />

(RI =0.54)

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