Guide for the Care and Use of Laboratory Animals - Office of ...

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IndexAAcclimation and adaptation, 111, 188(see also Procedural habitation andtraining)caloric management and, 67to noise and vibrations, 81-82to outdoor housing, 44, 54-55to physical restraint, 29Acquisition of animals (see Procurement)Activity and exercise, xiv, 43, 52-53, 55,56, 57, 58, 63-64, 67, 84 (see alsoEnrichment)Agricultural animals, 2biomedical vs. agricultural research,32-33environment and housing, 29, 33, 43,44, 137, 176-177floor drains, 137, 138information resources, 33, 176-177,191-192protocol review, 32-33space requirements, 60, 62-63surgery, 117, 144, 145veterinary care, 145, 191-182Air pressure, 45, 47, 139, 145-146, 149-150Air quality and airborne contaminants,45-47Airflow (see Ventilation and airflow)Albino animals, 48-49, 141Allergens and allergic reactions, 18, 19, 20,22-23, 45, 155Alternatives to laboratory animal use, 3, 5,12, 25, 27, 162-167American Association for Laboratory AnimalScience, 16American College of Laboratory AnimalMedicine, 24Guidelines for Adequate Veterinary Care,xvii, 14Ammonia, 45, 47, 68, 70, 71, 72-73, 78,79, 80, 81, 85Amphibians, 41-42, 44-45, 46, 77, 78-79,80, 81, 82, 83, 84, 85, 108, 119,156, 178-179, 192 (see also Aquaticspecies)Anesthesia and analgesiaconsiderations in selection of agents, 75,121equipment/delivery, 34, 122, 145, 147euthanasia agent, 124field conditions, 32, 117monitoring, 119-120, 122, 123neuromuscular blocking agents, 122-123oversight, 34, 156pain management, 12, 121-122preemptive analgesia, 121principles governing use, 12, 14, 26recommended reading, 188-190recordkeeping, 3420
210 INdEXsurgery, 115, 116, 117, 118, 119-120,122-123, 145, 188-190training, 17, 106, 115, 122waste gas management, 21, 147Animal and Plant Health Inspection Service(APHIS), 30, 148Animal care and use programattending veterinarian, 14collaborations, 15defined, 6disaster planning and emergencypreparedness, 35IACUC, 14-15, 24-33institutional official, 13-14oversight, 24-34personnel management, 15-24program management, 13-24recommended reading, 167-172regulations, policies, and principles,12-13responsibilities, 13-15Animal care personnel, (see also Personnel)training and education, 16Animal training (see Procedural habituationand training)Animal Welfare Act, 1, 4, 25, 34, 199Animal Welfare Information Center, xv, 16Animal Welfare Regulations, 1, 12housing guidelines, 56, 59IACUC, 25transportation of animals, 107veterinary care, 30Antibiotics, 116Anxiolytics, 122-123Apes (see Nonhuman primates)Aquatic species, 2 (see also Amphibians;Fish; Reptiles)algal growth, 86behavior and social management, 84diseases, 112emergency, weekend, and holiday care,87enrichment and social housing, 82-83environment, 77-82facilities, 150-151food and feeding, 84-85housing, 82-83, 150-151husbandry, 84-87identification, 87illumination, 81life support system, 79-80macroenvironment, 77-78, 86management, 84-88microenvironment, 77-78, 82-83noise and vibration, 81-82pest control, 87population management, 87-88recommended reading, 178-179,192-193recordkeeping, 87-88sanitation, 85-86sheltered, outdoor, and naturalistichousing, 83space, 83substrates, 85temperature, humidity, and ventilation,80-81water quality, 78-79, 85Aseptic practices, 17, 34, 52, 70, 75, 115,116, 117, 118-119, 144Attending veterinarian, 3, 4, 13, 14, 15, 17,21, 24, 28, 106, 114, 116 (see alsoVeterinary care)Autoclavingbedding material, 69, 146drinking water, 146feed, 66, 146surgical instruments, 119, 145Avian species (see Birds)Bacterial gill disease, 112Barriersaccess control, 151facilities, 113, 136, 145-146separation of housing and research/surgery areas, 134, 144visual, 51, 53, 83Bedding, nesting, and substratesaquatic species, 85autoclaving, 69, 136, 146behavioral aspects, 52changing, 46, 47, 52, 69, 70, 73disposal, 19, 20enrichment aspects, 67environmental aspects, 43, 44, 46, 47,49, 52, 53, 69, 71experimental influences, 68, 69illumination and, 49materials, 68-69outdoor facilities, 54storage, 136, 141terrestrial species, 52, 68-69b
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GUIDEFOR THE CARE AND USE OFLABORAT
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The National Academy of Sciences is
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MembersINSTITUTE FOR LAbORATORy ANI
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INSTITUTE FOR LAbORATORy ANIMAL RES
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PrefaceThe purpose of the Guide for
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PREFACExwho soon recognized that th
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xiiiOVERVIEWing the growing role of
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Contents1 KEy CONCEPTS 1Applicabili
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CONTENTSxxiiiAquatic Management, 84
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VETERINARy CARE 111Depending on the
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VETERINARy CARE 121(all), anorexia
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VETERINARy CARE 125Arndt SS, Lohave
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VETERINARy CARE12Haines DC, Gorelic
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