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ANIMAL CARE ANd USE PROGRAM3Olfert ED, Godson DL. 2000. Humane endpoints for infectious disease animal models. ILARJ 41:99-104.OSHA [Occupational Safety and Health Administration]. 1998a. Occupational Safety andHealth Standards. Subpart G, Occupational Health and Environmental Controls (29 CFR1910). Washington: Department of Labor.OSHA. 1998b. Occupational Safety and Health Standards. Subpart Z, Toxic and Hazardous Substances,Bloodborne Pathogens (29 CFR 1910.1030). Washington: Department of Labor.OSHA. 1998c. Occupational Safety and Health Standards. Subpart G, Occupational Healthand Environmental Controls, Occupational Noise Exposure (29 CFR 1910.95). Washington:Department of Labor.OSHA. 1998d. Occupational Safety and Health Standards. Subpart I, Personal Protective Equipment,Respiratory Protection (29 CFR 1910.134). Washington: Department of Labor.Paster EV, Villines KA, Hickman DL. 2009. Endpoints for mouse abdominal tumor models:Refinement of current criteria. Comp Med 59:234-241.PHS [Public Health Service]. 2002. Public Health Service Policy on Humane Care and Useof Laboratory Animals. Department of Health and Human Services, National Institutesof Health, Office of Laboratory Animal Welfare. Available at http://grants.nih.gov/grants/olaw/references/phspol.htm; accessed January 14, 2010.PL [Public Law] 104-191. 1996. Health Insurance Portability and Accountability Act (HIPAA)of 1996. Washington: Government Printing Office.PL 107-56. 2001. Uniting and Strengthening America by Providing Appropriate Tools Requiredto Intercept and Obstruct Terrorism (USA PATRIOT) Act of 2001. Washington: GovernmentPrinting Office. October 26.PL 107-188. 2002. Public Health Security and Bioterrorism Preparedness and Response Act of2002. Washington: Government Printing Office. June 12.Plante A, James ML. 2008. Program oversight enhancements (POE): The big PAM. ILAR J49:419-425.Prescott MJ, Buchanan-Smith HM. 2003. Training nonhuman primates using positive reinforcementtechniques. J Appl Anim Welf Sci 6:157-161.Pritt S, Duffee N. 2007. Training strategies for animal care technicians and veterinary technicalstaff. ILAR J 48:109-119.Reeb-Whitaker CK, Harrison, DJ, Jones RB, Kacergis JB, Myers DD, Paigen B. 1999. Controlstrategies for aeroallergens in an animal facility. J Allergy Clin Immunol 103:139-146.Reinhardt V. 1991. Training adult male rhesus monkeys to actively cooperate during inhomecagevenipuncture. Anim Technol 42:11-17.Reinhardt V. 1995. Restraint methods of laboratory non-human primates: A critical review.Anim Welf 4:221-238.Richmond JY, Hill RH, Weyant RS, Nesby-O’Dell SL, Vinson PE. 2003. What’s hot in animalbiosafety? ILAR J 44:20-27.Rowland NE. 2007. Food or fluid restriction in common laboratory animals: Balancing welfareconsiderations with scientific inquiry. Comp Med 57:149-160.Sargent EV, Gallo F. 2003. Use of personal protective equipment for respiratory protection.ILAR J 44:52-56.Sass N. 2000. Humane endpoints and acute toxicity testing. ILAR J 41:114-123.Sauceda R, Schmidt MG. 2000. Refining macaque handling and restraint techniques. LabAnim 29:47-49.Schweitzer IB, Smith E, Harrison DJ, Myers DD, Eggleston PA, Stockwell JD, Paigen B, SmithAL. 2003. Reducing exposure to laboratory animal allergens. Comp Med 53:487-492.Seward JP. 2001. Medical surveillance of allergy in laboratory animal handlers. ILAR J 42:47-54.Silverman J, Sukow MA, Murthy S, eds. 2007. The IACUC Handbook, 2nd ed. Boca Raton,FL: CRC Press.
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GUIDEFOR THE CARE AND USE OFLABORAT
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The National Academy of Sciences is
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MembersINSTITUTE FOR LAbORATORy ANI
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INSTITUTE FOR LAbORATORy ANIMAL RES
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ReviewersThis eighth edition of the
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PrefaceThe purpose of the Guide for
Page 16: PREFACExwho soon recognized that th
Page 19 and 20: xiiiOVERVIEWing the growing role of
Page 22 and 23: Contents1 KEy CONCEPTS 1Applicabili
Page 24 and 25: CONTENTSxxiiiAquatic Management, 84
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4Veterinary CareVeterinary care is
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VETERINARy CARE10from these sources
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VETERINARy CARE10In all cases, appr
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VETERINARy CARE 111Depending on the
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VETERINARy CARE 113and serology. If
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VETERINARy CARE 115RecordkeepingMed
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VETERINARy CARE11traffic (AORN 2006
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VETERINARy CARE11Specific steriliza
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VETERINARy CARE 121(all), anorexia
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VETERINARy CARE 123used in combinat
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VETERINARy CARE 125Arndt SS, Lohave
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VETERINARy CARE12Haines DC, Gorelic
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VETERINARy CARE12Morton CM, Reid J,
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VETERINARy CARE 131Stoskopf MK. 199
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156 AddENdUM4. Page 32. Original se
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Appendices
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appendixBU.S. Government Principles
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appendixCStatement of TaskThe use o
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appendixDAbout the AuthorsJanet C.
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APPENdIX d: AbOUT ThE AUThORS 205of
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APPENdIX d: AbOUT ThE AUThORS20Amer
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IndexAAcclimation and adaptation, 1
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INdEX 211Behavioral and social mana
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INdEX 213Disinfection, 20, 51, 52,
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INdEX 215Hydrogen peroxide, 72Hygie
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INdEXrecommended reading, 169-170re
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INdEX21pain and distress, 121-122re
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