198 Topics in Current Chemistry Editorial Board: A. de Meijere KN ...
198 Topics in Current Chemistry Editorial Board: A. de Meijere KN ...
198 Topics in Current Chemistry Editorial Board: A. de Meijere KN ...
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204 M.R. Caira<br />
angle which matches that of the substrate ledge site. Successful application of<br />
this pr<strong>in</strong>ciple to the selective nucleation and growth of a thermodynamically<br />
less favoured polymorph of a complex organic salt on succ<strong>in</strong>ic acid s<strong>in</strong>gle<br />
crystals as substrates has recently been reported [169].<br />
The approaches outl<strong>in</strong>ed above cont<strong>in</strong>ue to provi<strong>de</strong> new <strong>in</strong>sights <strong>in</strong>to the<br />
fundamental process of crystallization of organic molecules and studies of the<br />
type <strong>de</strong>scribed promise to contribute very significantly <strong>in</strong> the future to a <strong>de</strong>tailed<br />
un<strong>de</strong>rstand<strong>in</strong>g of the molecular orig<strong>in</strong>s of crystal polymorphism and to its<br />
effective control. The author believes that the phenomenon of polymorphism<br />
will, notwithstand<strong>in</strong>g such progress, reta<strong>in</strong> its aura as a remarkable manifestation<br />
of Nature’s diversity.<br />
Acknowledgements. My thanks are due to my colleague Prof L R Nassimbeni for constructive<br />
comments and to Fiona Jones for assistance with library resources. Research support from the<br />
University of Cape Town and the FRD (Pretoria) is gratefully acknowledged.<br />
5<br />
References<br />
1. Mitscherlich E (1822) Ann Chim Phys 19:350<br />
2. Dunitz JD (1996) In: Desiraju GR (ed) The crystal as a supramolecular entity:perspectives<br />
<strong>in</strong> supramolecular chemistry, vol 2. Wiley, New York, p 2<br />
3. Desiraju GR (<strong>198</strong>9) Crystal eng<strong>in</strong>eer<strong>in</strong>g. Elsevier, Amsterdam<br />
4. Sato K (1993) J Phys D: Appl Phys 26:B77<br />
5. Dunitz JD, Bernste<strong>in</strong> J (1995) Acc Chem Res 28:193<br />
6. Herbste<strong>in</strong> FH (1996) J Mol Struct 374:111<br />
7. Greenberg JH (1996) Mater Sci Eng R16:223<br />
8. Bayard F, Decoret C, Royer J (1990) Stud Phys Theor Chem 69:211<br />
9. Hernqvist L (1990) Food Struct 9:39<br />
10. Kalman A, Argay G (1991) Kem Kozl 73:129<br />
11. Bernste<strong>in</strong> J (1991) Polymorphism and the <strong>in</strong>vestigation of structure-property relations <strong>in</strong><br />
organic solids. In: Garbarczyk JB, James DW (eds) Organic crystal chemistry. Oxford<br />
University Press, Oxford, chap 2<br />
12. Cecch<strong>in</strong>i MAG (1992) Publ. ACIESP 82:65<br />
13. Bernste<strong>in</strong> J (1993) J Phys D: Appl Phys 26:B66<br />
14. Poole PH, Gran<strong>de</strong> T, Sciort<strong>in</strong>o F, Stanley HE, Angell CA (1995) Comput Mater Sci 4:373<br />
15. Lotz B (1995) Macromol Symp 94:97<br />
16. Bernste<strong>in</strong> J, Davis RE, Shimoni L, Chang N-L (1995) Angew Chem Int Ed Engl 34:1555<br />
17. Wolff JJ (1996) Angew Chem Int Ed Engl 35:2195<br />
18. Ford JL, Timm<strong>in</strong>s P (<strong>198</strong>9) Pharmaceutical thermal analysis, 1st edn. Ellis Horwood<br />
Limited, Chichester<br />
19. Byrn SR, Tobias B, Kessler D, Frye J, Sutton P, Sa<strong>in</strong>don P, Kozlowski J (<strong>198</strong>9) Trans Am<br />
Crystallogr Assoc 24:41<br />
20. Borka L, Haleblian JK (1990) Acta Pharm Jugosl 40:71<br />
21. Borka L (1990) Spectroscopy (Eugene, Oreg) 5:12<br />
22. Mehta AC (1994) Anal Proc 31:245<br />
23. Giron D (1995) Thermochim Acta 248:1<br />
24. Laird T (1990) In: Kennewell PD (ed) Comprehensive medic<strong>in</strong>al chemistry, vol 1. Pergamon,<br />
Oxford, p 321<br />
25. Curry SH, Thakker KM (1990) In: Taylor JB (ed) Comprehensive medic<strong>in</strong>al chemistry,<br />
vol 5. Pergamon, Oxford, p 545