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Challenges and Opportunities for Innovation in the Public Works ...

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Institutional risk control: High.<br />

Institutional exposure to fiduciary liability: Low to moderate <strong>for</strong> <strong>the</strong> <strong>in</strong>stitution; very<br />

high <strong>for</strong> <strong>the</strong> related entity.<br />

Institutional exposure to product liability: Low to moderate <strong>for</strong> <strong>the</strong> <strong>in</strong>stitution; high<br />

<strong>for</strong> <strong>the</strong> related entity.<br />

3. Commercialization through sp<strong>in</strong>-off companies controlled by an entity<br />

related to <strong>the</strong> Institution.<br />

F<strong>in</strong>ally, <strong>the</strong>re is <strong>the</strong> model of a related entity controlled by <strong>the</strong> agency or <strong>in</strong>stitution<br />

that does not engage <strong>in</strong> commercial activity itself but ra<strong>the</strong>r licenses <strong>the</strong> rights to a<br />

discovery to a sp<strong>in</strong>-off company that is <strong>the</strong>n capitalized <strong>and</strong>, usually as a jo<strong>in</strong>t venture with<br />

a commercial partner, br<strong>in</strong>gs <strong>the</strong> discovery <strong>in</strong>to <strong>the</strong> stream of commerce. Typically, when<br />

<strong>the</strong> discovery is successfully commercialized, <strong>the</strong> sp<strong>in</strong>-off company is sold to <strong>the</strong><br />

commercial partner, with <strong>the</strong> <strong>in</strong>stitution (through its related entity) receiv<strong>in</strong>g <strong>the</strong> capital<br />

appreciation. There are many models <strong>for</strong> this type of enterprise which may use jo<strong>in</strong>t<br />

ventures, various corporate <strong>for</strong>ms <strong>and</strong> limited partnerships to accomplish <strong>the</strong>ir purposes.<br />

The <strong>in</strong>stitution may own a major share of <strong>the</strong> equity of <strong>the</strong> sp<strong>in</strong>-off, ei<strong>the</strong>r directly or<br />

through an <strong>in</strong>termediary, although as <strong>the</strong> commercialization process progresses <strong>the</strong><br />

<strong>in</strong>stitution's <strong>in</strong>terest <strong>in</strong> <strong>the</strong> sp<strong>in</strong>-off may decl<strong>in</strong>e. The relative degree of <strong>in</strong>stitutional<br />

ownership may sicnificantly affect <strong>the</strong> exposure of <strong>the</strong> <strong>in</strong>stitution.<br />

This approach has <strong>the</strong> follow<strong>in</strong>g attributes:<br />

Value <strong>for</strong> capital <strong>for</strong>mation:Very high.<br />

Commercialization flexibility: Very high.<br />

Benefit to <strong>the</strong> <strong>in</strong>stitution: Very high.<br />

Benefit to <strong>the</strong> <strong>in</strong>vestigator: Varies, but usually high.<br />

Adm<strong>in</strong>istrative burden: Low to <strong>the</strong> <strong>in</strong>stitution; high to very high <strong>for</strong> <strong>the</strong> related<br />

<strong>in</strong>termediary entity.<br />

Institutional risk control: High.<br />

Institutional exposure to fiduciary liability: Low to moderate <strong>for</strong> <strong>the</strong> <strong>in</strong>stitution;<br />

moderate <strong>for</strong> <strong>the</strong> <strong>in</strong>termediary entity.<br />

Institutional exposure to product liability: Low <strong>for</strong> <strong>the</strong> <strong>in</strong>stitution; moderate <strong>for</strong> <strong>the</strong><br />

<strong>in</strong>termediary entity.<br />

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