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ReseaRch Quality assuRance foR the futuRe a ... - Lund University

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Panel 10 – medicine | Laboratory<br />

4. Stem Cell Center <strong>Lund</strong><br />

4.1 Overall assessment and infrastructure<br />

The Stem Cell Center was initiated approximately 6 years ago. It was<br />

directed until recently by Prof Sten Eirik Jacobsen an established investigator<br />

in <strong>the</strong> field of hematopoietic stem cells. Since <strong>the</strong> departure of<br />

Prof Jacobsen, Dr. Henrik Semb was appointed as interim director. Prof.<br />

Semb is an established investigator in beta cell biology and differentiation<br />

of embryonic stem cells (ESC) to beta cells.<br />

The Stem Cell Center is comprised of a number of well established<br />

basic researchers, a number of young promising scientists, and a smaller<br />

number of investigators in translational research with appointments both<br />

in <strong>the</strong> Faculty and <strong>the</strong> <strong>University</strong> Hospital, encompassing <strong>the</strong> fields of<br />

hematopoietic stem cells (HSC), hematopoietic and neural cancer stem<br />

cells (CSC), neural stem cells and neurobiology (NSC) and developmental<br />

biology. In addition, a program exists in functional genomics and<br />

computational biology, which also serves as a core facility to <strong>the</strong> larger<br />

<strong>University</strong> Community. Core facilities are also present within <strong>the</strong> Center<br />

for FACS, genetic mouse models and gene transfer are present. Among<br />

<strong>the</strong> faculty are 7 full professors, 8 researchers and 2 senior lecturers.<br />

The Center has done extremely well during <strong>the</strong> first period of its existence,<br />

with<br />

1. recruitment of a number of outstanding young investigators in <strong>the</strong><br />

different subprograms, both by international searches and from<br />

within <strong>the</strong> own ranks<br />

2. very significant external funding (50,600 MSEK in 2007) has been<br />

obtained, of which more than 42,000 MSEK in external grant<br />

funding. This includes funding as one of <strong>the</strong> 10 CoEs in Sweden and<br />

organization (?)/ and 5,000 MSEK from participation in European<br />

funding schemes; In addition <strong>the</strong> Center was awarded a Linne award<br />

3. scientists within <strong>the</strong> Center have published cutting edge science<br />

in outstanding journals, 6 of which in journals with IF of >20 in a<br />

number of <strong>the</strong> programs; and a large number of papers in journals<br />

with IF>10<br />

4. 54 PhD students are in training at <strong>the</strong> institute.<br />

293

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