health and safety plan solid waste management unit assessment

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HYDRAULIC FLUID 68-25
68.3.2.2 Chronic Toxicologic Effects
No studies were found in the literature dealing with the effects
of long-term exposure to hydraulic fluid oil in humans.
68.3.3 Toxicology of Hydraulic Fluid Components
The composition of hydraulic fluid varies greatly and usually
depends upon the specific conditions of use. Since the exact
composition of the oils is constantly changing.and difficult to define,
the toxicology of component classes are briefly discussed below. See
Table 68-4 for the acute toxicity data of specific compounds.
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Organic esters generally found in lubricating oils and hydraulic
fluids include a&pates, sebacates and dibasic acid esters. Dibasic
acid esters are primarily non-toxic via ingestion or skin absorption.
The only effect noted from dermal contact may be .a drying of the skin
(1822). Di(2-hexoxyethyl)succinate is a sebacate which is relatively
non-toxic to animals. In humans it is expected to have a low toxicity.
Large doses may produce CNS depression, nausea, vomiting and transient
liver and kidney injury (12). Not all neopentyl esters have been
tested for toxicity, but studies with trimethylopropane ester showed a
toxic level comparable to that of mineral oil (1822).
Ingestion of polyglycols is unlikely, but small amounts produce no
toxic effect. No cases of skin irritation or skin sensitization have
been reported; mild irritation to the eyelid has been reported but
effects were only transitory. Usually no inhalation hazard exists but
at high temperatures, where vapors are likely to form, adequate
ventilation should be provided (1822).
Ucor@ fluids are a mixture of polyalkylene glycols and diestars.
50-HB-260, 50-HB-5100, 25-H-2005 and 75-H-1400 are low in single-dose
oral toxicity with LD,, values for the male rat ranging from 5.95 to
>64 mL/kg bw; oral LD,, values for the rabbit range from 1.77 to 35.4
mL/kg bw. The lower molecular weight compounds are more toxic. A
dose-related .granular degeneration of the cytoplasm of the smooth
muscle in the intestinal wall was noted in dogs fed 25-H-2005 for 2
years. The significance of this finding is unknown. No other adverse
effects were shown. The only adverse effect observed in rats fed up to
0.5 g/kg/day of 25-H-2005 for two years was a slight growth depression
in females (12).
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