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health and safety plan solid waste management unit assessment

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METHYL ETHYL KETONE 41-11<br />

The movement of methyl ethyl ketone in ground water may result in<br />

discharge to surface water. As a result, ingestion exposures may occur<br />

resulting from the use of surface waters as drinking water supplies,<br />

<strong>and</strong> dermal exposures may result from the recreational use of surface<br />

waters. Such exposures are likely to be lower than those from drinking<br />

contaminated ground water due to biodegradation <strong>and</strong>/or volatilization<br />

of methyl ethyl ketone in surface water. Any pathways related to the<br />

uptake by aquatic organisms or domestic animals from surface waters are<br />

likely to be less significant than other sources of exposure due to the<br />

low BCF for methyl ethyl ketone.<br />

41.2.4 Other Sources of Human Exposure<br />

Methyl ethyl ketone is widely used as a industrial solvent,<br />

coating, <strong>and</strong> adhesive. As such, there are a number of sources of human<br />

exposure. Data, however, are somewhat lacking. For example, it is not<br />

commonly measured in drinking water.<br />

The production <strong>and</strong> use of methyl ethyl ketone has led to iis<br />

presence in the atmosphere. Brodzinksy <strong>and</strong> Singh (84) summarized air<br />

monitoring data for a number of pollutants. For methyl ethyl ketone,<br />

they<br />

for<br />

reported 181 data points<br />

these samples were less<br />

for<br />

than<br />

urban/suburban<br />

the detection<br />

areas.<br />

limit.<br />

All<br />

In<br />

results<br />

sourcedominated<br />

areas, the median concentration reported was 0.19 pg/m3 for<br />

33 data points.<br />

Dermal exposure is expected to be coaunon due to the prevalence of<br />

methyl ethyl ketone as a solvent in various products. For example, two<br />

surveys were conducted in Japan on the solvent content of a variety of<br />

products. They found methyl ethyl ketone in 26% of the paints, 21% of<br />

the inks, 23% of the adhesives, 11% of the thinners, <strong>and</strong> 8% of the<br />

degreasers that were sampled. While most of these products were used<br />

in occupational settings, some &y be used by consumers (1140,1141).<br />

The ketones are naturally occurring components of food. L<strong>and</strong>e &<br />

A. (1137) reviewed the literature <strong>and</strong> found methyl ethyl ketone in a<br />

wide variety of foods including cheese (0.3 ppm), milk (0.08 ppm),<br />

cream (0.2 ppm), bread, oranges <strong>and</strong> rum. This compound appears to be a<br />

common component of the diet although a total exposure from this source<br />

can not be evaluated without additional data (‘1137).<br />

41.3 HUMAN HEALTH CONSIDERATIONS<br />

41.3 .l Animal Studies<br />

41.3.1.1 Carcinogenicity<br />

No data were available with regard to the carcinogenic potential<br />

of methyl ethyl ketone.<br />

5/87<br />

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