health and safety plan solid waste management unit assessment
health and safety plan solid waste management unit assessment
health and safety plan solid waste management unit assessment
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
HYDRAULIC FLUID 68-28<br />
transient irritation with complete clearing after 48 hours. When<br />
inhaled at 4400 QQID for 19 to 26 days, HMS caused slight depression in<br />
the rat <strong>and</strong> guinea pig, with a very slight increase in rat liver <strong>and</strong><br />
kidney weights (12,13).<br />
Silicone resins had no influence on <strong>health</strong> when fed for 94 days to<br />
rats, <strong>and</strong> did not result in irritation to rabbit skin or eyes. No<br />
toxic effects were reported when injected into rats intraperitoneally<br />
(12) *<br />
Rats fed a dietary level of 0.30 Antifoam A0 for 2 years showed no<br />
significant toxic effect. Long-term feeding studies in mice reported<br />
similar results; however, a single subcutaneous injection of 0.2 mL<br />
antifoam showed a greater incidence of cysts at the site of injection<br />
(13).<br />
Polydimethyl siloxane caused no evident changes when tested for<br />
reQrOduCtiVe <strong>and</strong> teratologic effects in rats <strong>and</strong> rabbits, or testicular<br />
effects in rabbits. Dfmethylphenylmethylpolysiloxane, tris(trimethylsiloxy)phenylsilane<br />
<strong>and</strong> trifluoropropropylmethylpolysiloxane were<br />
also negative in male reproductive studies (13).<br />
Other components of hydraulic fluids include polyphenyl ethers.'<br />
Studies with phenyl ether show no toxicological effects following<br />
inhalation of vapors or contact with skin. Biq(p-phenoxyphenyl)ether,<br />
bis(m-phenoxyphenyl)ether, <strong>and</strong> n-bis(m-phenoxyphenoxy)benzene cause no<br />
irritation in skin tests with rabbits <strong>and</strong> only mild transient<br />
irritation in acute eye tests. These compounds were practically<br />
non-toxic in acute oral <strong>and</strong> intraperitoneal tests with rats. Phenolic<br />
degradation QrOduCtS formed during use of these materials under severe<br />
conditions are expected to increase toxicity (1822).<br />
HN Fluid Additives<br />
Information available on additives used in hydraulic fluid is<br />
limited. Selected compounds are briefly discussed below. Refer to<br />
Table 68:s for the acute toxicity data of specific additives.<br />
2,6-Di-tert-butyl-p-cresol, more commonly known as butylated<br />
hydroxytoluene or BHT, is used as an oxidation inhibitor in synthetic<br />
crankcase oil <strong>and</strong> hydraulic fluids.<br />
BHT inhibits tumorlgenesis when multiple doses are administered<br />
before a carcinogen while the incidence of hepatomas induced by<br />
2-acetylaminofluorene <strong>and</strong> the nuber of pulmonary adenomas induced by<br />
urethane were augmented by post-treatment with BHT (17). The NC1<br />
bioassay for carcinogenic effects of BHT in rats <strong>and</strong> mice was negative<br />
(17).<br />
6/87
Change language