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health and safety plan solid waste management unit assessment

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-T------ ‘I<br />

NEL OILS 66-29<br />

Anthracene<br />

Anthracene asserts phototoxic <strong>and</strong> photoallergic action on the<br />

human skin. It is carcinogenically inactive (l-2) . Various<br />

mutagenicity studies have produced negative responses (2315). 'Ihe<br />

lowest toxic oral dose in the rat is 20 g/kg (47).<br />

66.3.4 Toxicology of Fuel Oil Additives<br />

The toxicity of selected fuel oil additives is outlined below.<br />

Manvanese<br />

Comnoundq<br />

Manganese affects the CNS. Intoxication occurs mostly in the<br />

chronic form known as manganism which is similar to Parkinsonism.<br />

Usually manganism occurs after l-2 years exposure to manganese oxides<br />

although it may develop after only a few months. Initial symptoms<br />

include headache, asthenia (loss .of strength <strong>and</strong> energy), restless<br />

sleep <strong>and</strong> personality change. This is followed by an intermediate<br />

phase with visual hallucinations, double vision, impaired hearing,<br />

uncontrollable impulses, mental confusion <strong>and</strong> euphoria. In advanced<br />

stages, the patient experiences excessive salivation, muscle weakness,<br />

muscle rigidity, tremor of the upper extremities <strong>and</strong> head, <strong>and</strong> impaired<br />

gait. In manganism with neurologic symptoms, the course is frequently<br />

progressive although some cases are stationary <strong>and</strong> others recover<br />

(2946).<br />

Inhalation of high concentrations of manganese oxide causes metal<br />

fume fever - a 24-48 hour illness characterized by chills, fever,<br />

aching muscles, dry mouth <strong>and</strong> throat, <strong>and</strong> headache (46).<br />

Magnesium oxide fumes are irritating to the eyes <strong>and</strong> nose. It<br />

also causes metal fume fever which is a 24-48 hour influenza-type<br />

illness (46).<br />

.<br />

Aluminum<br />

Oxide<br />

Aluminum oxide is a nuisance dust which has little adverse effect<br />

on the lungs at low exposure levels. Excessive concentrations may<br />

cause deposits in the eyes, ears <strong>and</strong> nasal passages or may cause mild<br />

injury to the skin <strong>and</strong> mucous membranes (46).<br />

Peroxidea<br />

In general, peroxides are strong oxidizing agents capable of skin<br />

irritation, bums or eye damage (200).<br />

6/87

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