NASA Scientific and Technical Aerospace Reports

20040111584 State Univ. of New York, Stony Brook, NY
Innovative Surveillance and Risk Reduction Systems for Family Maltreatment, Suicidality and Substance Problems in
the USAF
Slep, Amy M.; Mar. 2004; 179 pp.; In English; Original contains color illustrations
Contract(s)/Grant(s): DAMD17-03-1-0166
Report No.(s): AD-A425647; No Copyright; Avail: CASI; A09, Hardcopy
This project aims to enhance the capacity of the Air Force (AP) to reduce death, injury, and degraded force readiness via
reduction of he prevalence and impact of family - maltreatment, suicidality, and alcohol/drug problems. Managing risk and
increasing resilience in military human resources (i.e., ‘Force-Health Protection") is a top priority for DoD and Armed
Forces leaders. The objective of this study is to enhance the AF’s current prevention delivery (known as the Integrated Deliver
System; IDS)infrastructure through (a) development and validation of an information system needed to direct prevention
efforts more effectively and efficiently; (b) adoption of a prevent ion-science-based approach; and (c) evaluation of its
effectiveness. When funded, the proposed project was broken into two phases. This first phase is a demonstration project on
which to build a randomized trial. This project includes: (a) pilot testing the development of an innovative surveillance system
and validating its accuracy (at 3AF bases) for family maltreatment, suicidality, and problematic alcohol and drug use, and (b)
pilot testing the creation of an enhanced IDS by training community leaders in prevent ion-science-based intervention
methodology and testing the impact on factors that are prerequisites for effective community prevention initiatives and on
targeted outcomes.
DTIC
Drugs; Health; Injuries; Risk; Stress (Psychology); Surveillance
20040111585 McKesson BioServices, Rockville, MD
Services to Operate and Maintain a Microwave Research Laboratory
Lu, Shin-Tsu; May 2004; 453 pp.; In English
Contract(s)/Grant(s): DAMD17-94-C-4069
Report No.(s): AD-A425649; No Copyright; Avail: CASI; A20, Hardcopy
Due to growing concerns for the health and safety of military and civilian personnel exposed to radiofrequency radiation
(RFR), a series of research have been performed at the U.S. Army Medical Research Detachment, Microwave Bioeffects
Branch at Brooks City-Base, Texas. The research has been concentrated on neurotoxic effects of high peak power but low
average power RFR, Interact ion between neurotoxin and RFR on manifestation of neurotoxic effects, effects of high power
RFR on hippocampus, biological hazards of ultra- wide-band (UWB) pulses on cardiovascular function and cell systems,
cytotoxic effect of nanosecond high-intensity electric pulses, finite difference time domain techniques for RFR dosimetry, role
of ambient temperature on manifestation of RFR induced biological effects, design fabrication and testing a circularly
polarized 1.25 GHz waveguide exposure system, and formulate a research plan for body borne and helmet mounted antennas.
Majority of results falls in ‘thermal’ effect, albeit, the threshold was at lower magnitude than that previously envisioned. A
model is devised to demonstrate the additive effect of RFR to thermal ‘stress’ from ambient environment. On the other hand,
some of the observed effects cannot be easily explained by the ‘thermal’ mechanism. They were effects of UWB pulses and
nanosecond high power electric pulses.
DTIC
Microwaves
20040111586 Alabama Univ., Birmingham, AL
Polyphenols and Prostate Cancer Chemoprevention
Lamartiniere, Coral A.; Mar. 2004; 5 pp.; In English
Contract(s)/Grant(s): DAMD17-03-1-0153
Report No.(s): AD-A425650; No Copyright; Avail: CASI; A01, Hardcopy
The polyphenols, catechin, (-)-epigallocatechin-3- gallate (EGCG), genistein and resveratrol, are associated with reduced
incidences of prostate and breast cancers. The goal of this research is to investigate the potential of these 3 pure polyphenols,
alone and in combination, to protect against prostate cancer in an animal model that spontaneously develops prostate cancer
(TRAnsgenic Mouse Prostate adenocarcinoma (TRAMP)). In this manner, it may be possible to ingest moderate amount of
each of these foods/chemicals, as opposed to mega amounts of one, and receive an additive or synergistic protective effect
without adverse effects with possible elevated exposure. The specific aims are 1) to investigate the potential of genistein,
EGCG and resveratrol, alone and in combination, to suppress the development of spontaneously developing prostate tumors
and 2) to investigate the potential of genistein, EGCG and resveratrol to regulate sex steroid- and specific growth
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