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NASA Scientific and Technical Aerospace Reports

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Using a Resource-Based Theory/View of the firm, this study examined if increased inpatient staffing levels at military<br />

hospitals can generate a competitive advantage based on better patient quality outcomes. Specifically, this study examined the<br />

relationships between levels of registered nurse staffing, nonregistered nurse staffing, <strong>and</strong> physician staffing to patient quality<br />

outcomes. Patient quality outcomes in this study were measured by average length of stay, in-house mortality rates, <strong>and</strong> 30-day<br />

readmission rates. The current study found some support that increasing nurse staffing, especially registered nurse staffing,<br />

does lead to better inpatient quality outcomes as defined by shorter average length of stay <strong>and</strong> lower inpatient mortality rates.<br />

DTIC<br />

Health; Medical Services<br />

20040111711 Miami Univ., FL<br />

Evaluation of Chemicals for Antimalarial Activity Against Blood <strong>and</strong> Tissue Stages<br />

Ager, Arba L.; Apr. 2004; 11 pp.; In English<br />

Contract(s)/Grant(s): DAMD17-03-2-0031<br />

Report No.(s): AD-A425867; No Copyright; Avail: CASI; A03, Hardcopy<br />

Two different test systems were used to detect antimalarial activity of new compound mice. The first test detected activity<br />

against blood stage parasites (Modified Thomp Test). There were 85 three level test done <strong>and</strong> 21 compounds exhibited activity<br />

against the asexual blood stages. The 2 most active compounds were BN 43115 <strong>and</strong> BQ 33897. The second test (SPZ Test)<br />

detected activity against the sporosoite stages or the exoerythrocytic schizont stages in the liver There were 100 three level<br />

tests done the most active compounds were BQ 11373, BQ 29286, BQ 35131, BQ 29339, BQ 11391 <strong>and</strong> 11391. A new oracle<br />

database was used to enter data from the Modified Thompson Test.<br />

DTIC<br />

Blood<br />

20040111712 Arizona Univ., Tucson, AZ<br />

A Chemopreventive Trial to Study the Effects of High Tea Consumption on Smoking-Related Oxidative Stress<br />

Hakim, Iman A.; Feb. 2004; 9 pp.; In English; Original contains color illustrations<br />

Contract(s)/Grant(s): DAMD17-03-1-0053<br />

Report No.(s): AD-A425871; No Copyright; Avail: CASI; A02, Hardcopy<br />

Our overall goal is to develop a sage <strong>and</strong> feasible model for the chemopreventive of a wide range of tobacco- related<br />

diseases. Our immediate goal, that is addressed over a 4-year study period, is to determine the effects of high tea consumption<br />

on biological markers of -oxidative stress that mediate lung cancer risk. We are conducting a 6-month r<strong>and</strong>omized, controlled,<br />

double-blinded chemopreventive trial in a group of COPD subjects who are being r<strong>and</strong>omized to green or black tea<br />

preparations or a control intervention (matching placebo). Levels of 8-hydroxydeoxyguanosine <strong>and</strong> 8-F2- isoprostanes will be<br />

use dot measure DNA <strong>and</strong> lipid damage respectively. Changes in biomarkers of oxidative damage will be measured in urine,<br />

blood, <strong>and</strong> exhaled breath condensate. The study protocol was approved by all parties in September 2003. Recruitment <strong>and</strong><br />

screening of participants for eligibility criteria-a started in October 2003. By the end of December, 28 participants signed the<br />

consent form <strong>and</strong> were screened for eligibility criteria (spirometry for lung function). Eight subjects with FEV1\g85% of. the<br />

st<strong>and</strong>ard were excluded for the study <strong>and</strong> 3 subjects dropped out. Currently 17 eligible subjects were enrolled in the study.<br />

Eleven subjects are completing the 1-month run-in period <strong>and</strong> 8 subjects have been r<strong>and</strong>omized. We expect that adherence to<br />

a regular pattern of tea is feasible <strong>and</strong> quantifiable among this high risk population.<br />

DTIC<br />

Smoke; Stress (Physiology); Tea Lasers; Tobacco<br />

20040111713 Wayne State Univ., Detroit, MI<br />

Undergraduate Summer Fellowships in Breast Cancer Research<br />

Brooks, Sam C.; Mar. 2004; 10 pp.; In English<br />

Contract(s)/Grant(s): DAMD17-02-1-0617<br />

Report No.(s): AD-A425878; No Copyright; Avail: CASI; A02, Hardcopy<br />

The Barbara Ann Karmanos Cancer Institute (KCI) is dedicated to training young scientists for careers in research. The<br />

intent of this application is to broaden the number of students that can participate in KCI’s undergraduate summer training<br />

program by creating a focused program utilizing the established Breast Cancer Program of our Comprehensive Cancer Center.<br />

It is our intent to recruit promising undergraduate science majors, give them the opportunity to take part in breast cancer<br />

research <strong>and</strong> impress them with the excitement of contributing to the cure/prevention of this dread disease. This summer<br />

211

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