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Encyclopedia of Health and Medicine

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The Reproductive System 237<br />

strual cycles. The ovaries contain a finite number<br />

<strong>of</strong> ova, present at birth. From the onset <strong>of</strong> MEN-<br />

STRUATION to midlife, each monthly cycle causes a<br />

half dozen to a dozen ovarian follicles to ripen.<br />

Usually only one ovum (egg) reaches full maturity<br />

<strong>and</strong> leaves the ovary; the others atrophy (shrink)<br />

<strong>and</strong> the ovary reabsorbs them. By midlife the<br />

ovaries have made it pretty much through their<br />

supply <strong>of</strong> ova, far fewer follicles activate with each<br />

MENSTRUAL CYCLE, <strong>and</strong> ovarian function begins to<br />

shut down. Over a period <strong>of</strong> five to eight years,<br />

menstrual cycles become irregular <strong>and</strong> eventually<br />

infrequent until they stop altogether.<br />

<strong>Health</strong> <strong>and</strong> Disorders <strong>of</strong> the Reproductive System<br />

The health <strong>of</strong> the reproductive system, male or<br />

female, experiences internal <strong>and</strong> external influences.<br />

Internally the reproductive system relies<br />

significantly on an intricate hormonal balance as<br />

hormones direct nearly all sexual <strong>and</strong> reproductive<br />

functions. Disorders are <strong>of</strong>ten endocrine in<br />

origin. The organs <strong>of</strong> reproduction are particularly<br />

vulnerable to cancers that thrive on hormones,<br />

such as BREAST CANCER, OVARIAN CANCER, ENDOME-<br />

TRIAL CANCER, PROSTATE CANCER, <strong>and</strong> TESTICULAR CAN-<br />

CER. Externally the reproductive system is<br />

vulnerable to injury <strong>and</strong> illness, to great extent<br />

through sexual activity. SEXUALLY TRANSMITTED DIS-<br />

EASES (STDS) can cause serious <strong>and</strong> sometimes lifethreatening<br />

health conditions. STDs are a leading<br />

cause <strong>of</strong> INFERTILITY in women <strong>and</strong> can cause illness<br />

in newborns who are exposed during birth. Other<br />

factors that can affect reproductive health include<br />

exposures to chemicals such as pesticides or to<br />

radiation, which can damage the DNA <strong>of</strong> sperm or<br />

ova.<br />

External factors are particularly important during<br />

pregnancy, when certain exposures at vulnerable<br />

points <strong>of</strong> fetal development can cause<br />

permanent injury. INFECTION with common viruses<br />

such as RUBELLA (German MEASLES) or measles can<br />

cause devastating BIRTH DEFECTS, as can taking certain<br />

drugs <strong>and</strong> medications. Nearly any substance<br />

the woman takes into her body may cross the PLA-<br />

CENTA to enter the fetus’s BLOOD circulation. FETAL<br />

ALCOHOL SYNDROME, a constellation <strong>of</strong> physical birth<br />

defects <strong>and</strong> developmental abnormalities that<br />

occurs as a result <strong>of</strong> fetal exposure to ALCOHOL, is<br />

entirely preventable.<br />

HEALTH CONDITIONS OF THE REPRODUCTIVE SYSTEM<br />

ADENOMYOSIS<br />

BALANITIS<br />

BENIGN PROSTATIC HYPERPLASIA<br />

(BPH)<br />

CERVICAL CANCER<br />

CHORDEE<br />

CRYPTORCHIDISM<br />

ECLAMPSIA<br />

ENDOMETRIAL CANCER<br />

ENDOMETRIOSIS<br />

ERECTILE DYSFUNCTION<br />

FIBROCYSTIC BREAST DISEASE<br />

HEMATOSPERMIA<br />

HYPOGONADISM<br />

INTRADUCTAL PAPILLOMA<br />

MASTALGIA<br />

NABOTHIAN CYST<br />

ORCHITIS<br />

OVARIAN CYST<br />

PARAPHIMOSIS<br />

PHIMOSIS<br />

PREECLAMPSIA<br />

PREMATURE OVARIAN FAILURE<br />

PRIAPISM<br />

PROSTATE CANCER<br />

SEXUAL DYSFUNCTION<br />

SPERMATOCELE<br />

TESTICULAR CANCER<br />

TURNER’S SYNDROME<br />

UTERINE PROLAPSE<br />

VARICOCELE<br />

AMENORRHEA<br />

BARTHOLIN CYST<br />

BREAST CANCER<br />

CANCER OF THE PENIS<br />

CERVICAL INTRAEPITHELIAL<br />

NEOPLASIA (CIN)<br />

DYSMENORRHEA<br />

ECTOPIC PREGNANCY<br />

ENDOMETRIAL HYPERPLASIA<br />

EPIDIDYMITIS<br />

fibroadenoma<br />

GYNECOMASTIA<br />

HYDROCELE<br />

INFERTILITY<br />

KLINEFELTER’S SYNDROME<br />

MASTITIS<br />

NEONATAL JAUNDICE<br />

OVARIAN CANCER<br />

PAGET’S DISEASE OF THE BREAST<br />

PEYRONIE’S DISEASE<br />

POLYCYSTIC OVARY SYNDROME<br />

(PCOS)<br />

PREMENSTRUAL SYNDROME<br />

(PMS)<br />

PROSTATITIS<br />

SEXUALLY TRANSMITTED DISEASES<br />

(STDS)<br />

TESTICULAR TORSION<br />

UTERINE FIBROIDS<br />

VAGINITIS<br />

VULVODYNIA<br />

Traditions in Medical History<br />

The high rate <strong>of</strong> maternal deaths from “childbirth<br />

FEVER” (puerperal fever) at the dawn <strong>of</strong> the era <strong>of</strong><br />

antisepsis motivated Hungarian obstetrician Ignaz<br />

Philipp Semmelweis (1818–1861) to change his<br />

habits. In so doing, he transformed the practice <strong>of</strong><br />

obstetrics <strong>and</strong> saved countless lives. By the middle<br />

<strong>of</strong> the 19th century scientists knew <strong>of</strong> the existence<br />

<strong>of</strong> microbes <strong>and</strong> their role in causing disease,<br />

though their mechanisms <strong>of</strong> infection remained a<br />

mystery. An emerging recognition was <strong>of</strong> the danger<br />

<strong>of</strong> infection for pathologists who performed<br />

autopsies. The slight wound from a slip <strong>of</strong> the<br />

scalpel was all too <strong>of</strong>ten fatal, causing systemic<br />

infection known as pathologist’s pyemia. Semmelweis<br />

was the first to connect the two apparently

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