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Encyclopedia of Health and Medicine

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340 The Reproductive System<br />

<strong>and</strong> QUALITY OF LIFE. STDs infect tens <strong>of</strong> millions <strong>of</strong><br />

people in the United States <strong>and</strong> hundreds <strong>of</strong> millions<br />

<strong>of</strong> people throughout the world.<br />

STDs may not have symptoms though the person<br />

continues to be infectious (capable <strong>of</strong> passing<br />

the STD to sex partners). Often a person has more<br />

than one STD at the same time, a circumstance<br />

called co-infection. It is possible for reinfection<br />

with the same STD to occur after treatment.<br />

ANTIBIOTIC MEDICATIONS are the mainstay <strong>of</strong> treatment<br />

for bacterial STDs. ANTIVIRAL MEDICATIONS<br />

may alleviate symptoms in viral STDs such as GEN-<br />

ITAL HERPES <strong>and</strong> lessen the risk for transmitting the<br />

VIRUS to others, though the virus <strong>of</strong>ten remains in<br />

the body <strong>and</strong> symptoms recur.<br />

Though all STDs are treatable, many are not<br />

curable. Some, such as HEPATITIS B <strong>and</strong> HUMAN<br />

PAPILLOMAVIRUS (HPV), are known causes <strong>of</strong> cancer<br />

(LIVER CANCER <strong>and</strong> CERVICAL CANCER, respectively).<br />

Hepatitis C may be fatal <strong>and</strong> at present HIV/AIDS is<br />

always fatal, though treatment <strong>and</strong> supportive<br />

lifestyle measures can manage both conditions for<br />

years to decades. STDs are a leading cause <strong>of</strong> PELVIC<br />

INFLAMMATORY DISEASE (PID) in women, a serious<br />

INFECTION that can result in INFERTILITY by causing<br />

scarring <strong>and</strong> occlusion (blockage) <strong>of</strong> the FALLOPIAN<br />

TUBES <strong>and</strong> sometimes the CERVIX.<br />

Oral contraceptives (birth control pills),<br />

intrauterine devices (IUDs), cervical<br />

diaphragms, spermicides, VASECTOMY,<br />

TUBAL LIGATION, <strong>and</strong> HYSTERECTOMY,<br />

though effective methods <strong>of</strong> CONTRACEP-<br />

TION, do not prevent INFECTION with SEX-<br />

UALLY TRANSMITTED DISEASES (STDS).<br />

Abstinence (no sexual partners) is the most<br />

effective means to prevent infection with STDs.<br />

Among people who are sexually active, key measures<br />

to reduce the risk for STD infection are<br />

• long-term, mutual monogamy (one exclusive<br />

sex partner)<br />

• male latex condom use with every sexual act<br />

(vaginal intercourse, anal intercourse, oral sex,<br />

partner MASTURBATION)<br />

The effectiveness <strong>of</strong> these measures varies for<br />

the specific STD. Latex condoms are highly effective<br />

for preventing GONORRHEA <strong>and</strong> HPV, for example,<br />

though may be less effective for protecting<br />

against genital herpes <strong>and</strong> HIV/AIDS. The female<br />

condom is another barrier method <strong>of</strong> CONTRACEPTION<br />

that provides some, but more limited, protection<br />

from STD infection compared to the male condom.<br />

Unprotected contact with bodily fluids (pre-ejaculate<br />

or vaginal secretions), such as may occur during<br />

heavy petting <strong>and</strong> foreplay, carries the same risk<br />

for STD infection as does actual intercourse.<br />

Infections not typically characterized as STDs,<br />

such as TUBERCULOSIS, may also pass between people<br />

during sexual activity. Conversely, some infections<br />

characteristically transmitted through sexual contact<br />

may also pass via other means such as shared<br />

needles among intravenous DRUG users (notably<br />

HIV/AIDS <strong>and</strong> hepatitis). An infant may acquire<br />

gonorrhea, CHLAMYDIA, <strong>and</strong> genital herpes during<br />

CHILDBIRTH (passage through the VAGINA). An infant<br />

may also acquire congenital herpes without passing<br />

through the birth canal if the mother first becomes<br />

infected when she is pregnant.<br />

Because many STDs are highly contagious <strong>and</strong><br />

prompt treatment can minimize their spread as<br />

well as prevent long-term health complications for<br />

infected individuals, health experts strongly<br />

encourage diagnostic testing <strong>and</strong> treatment for all<br />

sexual partners <strong>of</strong> everyone who acquires an STD.<br />

In the United States, community health centers<br />

<strong>and</strong> public health services provide low-cost or free<br />

STD testing <strong>and</strong> treatment. Private doctors <strong>and</strong><br />

other health-care providers also diagnose <strong>and</strong><br />

treat STDs.<br />

See also ANTIBIOTIC RESISTANCE; SEXUAL HEALTH;<br />

SEXUALLY TRANSMITTED DISEASE (STD) PREVENTION.<br />

sperm The male cells <strong>of</strong> reproduction, also called<br />

gametes. A spermatozoon (single sperm cell) is a<br />

haploid cell; it contains one half <strong>of</strong> the genetic<br />

material necessary for human life. The epididymis<br />

within the testicle (also called the testis) produces<br />

sperm, a process called spermatogenesis, at the rate<br />

<strong>of</strong> hundreds <strong>of</strong> millions each day from PUBERTY (the<br />

onset <strong>of</strong> sexual maturity) through the end <strong>of</strong> life.<br />

The tissues <strong>of</strong> the TESTICLES absorb sperm that<br />

remain in the epididymis for longer than six weeks,<br />

allowing the supply <strong>of</strong> sperm to remain fresh.<br />

Spermatogenesis The production <strong>of</strong> new sperm<br />

cells begins with the division <strong>and</strong> differentiation <strong>of</strong>

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