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Encyclopedia of Health and Medicine

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310 Lifestyle Variables: Smoking <strong>and</strong> Obesity<br />

MEDICATIONS TO SUPPRESS APPETITE<br />

Medication Actions Possible Side Effects<br />

orlistat (Xenical) blocks intestinal absorption <strong>of</strong> fat frequent or uncontrollable bowel movements<br />

deficiency <strong>of</strong> fat-soluble vitamins (A, D, E, <strong>and</strong> K)<br />

phentermine (Fastin) CENTRAL NERVOUS SYSTEM stimulant dependency<br />

increases NOREPINEPHRINE levels in the PALPITATIONS<br />

BRAIN, which suppresses the APPETITE <strong>and</strong> insomnia<br />

HUNGER centers<br />

DRUG INTERACTION with monoamine oxidase inhibitor<br />

(MAOI) antidepressants<br />

sibutramine (Meridia) increases norepinephrine <strong>and</strong> serotonin serotonin syndrome<br />

levels in the brain, an action that drug interaction with narcotic analgesics, selective<br />

suppresses the appetite <strong>and</strong> hunger serotonin reuptake inhibitor (SSRI) antidepressants, <strong>and</strong><br />

centers <strong>and</strong> elevates mood<br />

MAOI antidepressants<br />

Bariatric surgery Weight loss surgery is a drastic<br />

measure that becomes a treatment option<br />

when an individual’s weight exceeds 100 pounds<br />

over healthy weight (class 3 obesity) or otherwise<br />

directly <strong>and</strong> immediately threatens health. Most<br />

bariatric surgery operations either restrict the size<br />

<strong>of</strong> the STOMACH to limit the volume <strong>of</strong> consumed<br />

food or alter the flow <strong>of</strong> ingested food to curtail<br />

absorption. Surgery for weight loss has numerous<br />

risks <strong>and</strong> potential complications, though may be<br />

the therapeutic approach that succeeds for people<br />

who have been otherwise unable to reach a<br />

healthier weight.<br />

HEALTH BENEFITS OF WEIGHT LOSS<br />

decrease OSTEOARTHRITIS improve HYPERLIPIDEMIA<br />

symptoms<br />

improve HYPERTENSION<br />

improve INSULIN sensitivity improve LIBIDO <strong>and</strong> sexual<br />

relieve OBSTRUCTIVE SLEEP<br />

function<br />

APNEA<br />

improve self-esteem<br />

improve type 2 DIABETES improve FERTILITY<br />

increase energy <strong>and</strong> mobility reduce risk for cancer<br />

reduce risk for CARDIOVASCULAR reduce risk for type 2<br />

DISEASE (CVD)<br />

diabetes<br />

relieve chronic BACK PAIN relieve GASTROESOPHAGEAL<br />

REFLUX DISORDER (GERD)<br />

Maintaining <strong>Health</strong>y Body Weight<br />

Weight loss that is gradual <strong>and</strong> steady generally<br />

results from incorporating lifestyle changes that<br />

will support sustained weight management. Even<br />

small progress makes a measurable difference in<br />

health <strong>and</strong> well-being.<br />

Social <strong>and</strong> family support Encouragement <strong>and</strong><br />

support for weight loss <strong>and</strong> weight management<br />

from family <strong>and</strong> friends is crucial for long-term<br />

success, though is <strong>of</strong>ten a complex dynamic. Some<br />

people find themselves alone in their weight loss<br />

efforts because other family members do not want<br />

to make the same changes in their own eating<br />

habits <strong>and</strong> physical activity. Other people are able<br />

to make weight loss <strong>and</strong> weight management a<br />

family endeavor or to join with friends to support<br />

<strong>and</strong> encourage one another. Positive reinforcement<br />

for achievements, however small, is far<br />

more effective than criticism.<br />

Relapse <strong>and</strong> weight gain Relapses <strong>of</strong> regained<br />

weight are common <strong>and</strong> disheartening. However,<br />

the quicker a person recognizes that his or her<br />

weight is slipping back toward obesity the easier it<br />

is to stop the slide <strong>and</strong> return to the treatment<br />

methods that were effective. Unfortunately many<br />

people tend not only to regain lost weight but also<br />

to gain additional weight. Such a rebound or “yoyo”<br />

effect is especially detrimental to health. It is<br />

important to get back on track with eating habits<br />

<strong>and</strong> exercise as quickly as possible to halt weight<br />

gain before it becomes overwhelming to confront.<br />

See also DIET AND HEALTH; EATING DISORDERS; EXER-<br />

CISE AND HEALTH; OBESITY AND HEALTH.

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