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Encyclopedia of Health and Medicine

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penis 317<br />

procedures. The doctor closes the speculum’s<br />

blade to withdraw the speculum.<br />

See also KEGEL EXERCISES; PREVENTIVE HEALTH CARE<br />

AND IMMUNIZATIONS.<br />

pelvic inflammatory disease (PID) A bacterial<br />

INFECTION involving the UTERUS, FALLOPIAN TUBES,<br />

CERVIX, <strong>and</strong> VAGINA. Untreated PID has the potential<br />

to become life threatening if it spreads to<br />

involve the peritoneal membrane (PERITONITIS), the<br />

tissue that encloses the abdominal cavity. Because<br />

PID can cause scarring within the fallopian tubes<br />

that occludes them (blocks the tubes’ openings),<br />

chronic or recurrent PID is a leading cause <strong>of</strong><br />

INFERTILITY in women. PID is a significant health<br />

concern in the United States with doctors diagnosing<br />

more than one million women with it each<br />

year, about half <strong>of</strong> whom have permanently<br />

impaired FERTILITY as a consequence.<br />

The most common cause <strong>of</strong> PID is recurrent or<br />

untreated infection with SEXUALLY TRANSMITTED DIS-<br />

EASES (STDS) such as CHLAMYDIA <strong>and</strong> GONORRHEA.<br />

Other causes include infection that occurs as a<br />

postoperative complication after a surgical procedure<br />

such as DILATION AND CURETTAGE (D&C) or elective<br />

ABORTION. A less common cause <strong>of</strong> PID is<br />

infection resulting from an intrauterine device<br />

(IUD), a form <strong>of</strong> long-term birth control.<br />

Symptoms <strong>and</strong> Diagnostic Path<br />

It is possible to have PID, especially chronic PID,<br />

with few or no symptoms. Many women who<br />

have PID typically appear quite ill, however, <strong>and</strong><br />

may have FEVER <strong>and</strong> chills in addition to other<br />

symptoms. Such symptoms may include<br />

• yellowish or greenish malodorous (foulsmelling)<br />

vaginal discharge<br />

• lower abdominal tenderness, cramping, or PAIN<br />

• NAUSEA, VOMITING, <strong>and</strong> DIARRHEA<br />

• vaginal bleeding between menstrual periods<br />

• irregular or unusually heavy menstrual periods<br />

The diagnostic path includes PELVIC EXAMINATION<br />

with vaginal discharge <strong>and</strong> tissue samples for laboratory<br />

analysis <strong>and</strong> BLOOD tests to evaluate the<br />

presence <strong>of</strong> infection or INFLAMMATION within the<br />

body (such as elevated sedimentation rate, white<br />

blood cell count, <strong>and</strong> C-REACTIVE PROTEIN). The<br />

cervix <strong>and</strong> uterus are generally very tender to palpation<br />

during the pelvic exam, which is a key<br />

diagnostic criterion.<br />

Treatment Options <strong>and</strong> Outlook<br />

Treatment is prompt administration <strong>of</strong> ANTIBIOTIC<br />

MEDICATIONS, by intravenous (IV) or intramuscular<br />

injection for severe symptoms <strong>and</strong> orally otherwise.<br />

Antibiotic therapy may include two or more<br />

antibiotic medications, depending on the identified<br />

BACTERIA present in the vaginal <strong>and</strong> cervical<br />

cultures. It is essential to take the full course <strong>of</strong> all<br />

antibiotics as prescribed to completely eradicate<br />

the infection, which cures the PID. ANALGESIC MED-<br />

ICATIONS relieve pain <strong>and</strong> reduce fever to improve<br />

comfort. Possible complications <strong>of</strong> PID include<br />

infertility, increased risk for ECTOPIC PREGNANCY,<br />

<strong>and</strong> chronic pelvic pain. The likelihood <strong>of</strong> these<br />

complications increases with each episode <strong>of</strong> PID,<br />

though prompt diagnosis <strong>and</strong> treatment helps mitigate<br />

their risk.<br />

ANTIBIOTICS TO TREAT<br />

PELVIC INFLAMMATORY DISEASE (PID)<br />

ampicillin/sulbactam<br />

cefotetan<br />

cefoxitin<br />

ceftriaxone<br />

cipr<strong>of</strong>loxacin<br />

clindamycin<br />

doxycycline<br />

gentamicin<br />

metronidazole<br />

<strong>of</strong>loxacin<br />

Risk Factors <strong>and</strong> Preventive Measures<br />

The primary risk factor for PID is untreated STD<br />

infection. Many people do not have symptoms <strong>of</strong><br />

STDs yet are infected <strong>and</strong> pass the infections to<br />

their sex partners. Multiple sex partners <strong>and</strong><br />

unprotected sex are high-risk behaviors for STDs<br />

<strong>and</strong> PID. Measures to prevent infection among<br />

sexually active adults include mutual monogamy<br />

<strong>and</strong> latex condom use with every sexual act.<br />

See also HIV/AIDS; MENSTRUATION; SEXUALLY TRANS-<br />

MITTED DISEASE (STD) PREVENTION.<br />

penis The male organ for URINATION <strong>and</strong> SEXUAL<br />

INTERCOURSE. The penis is an elongated, cylindrical<br />

structure made <strong>of</strong> connective <strong>and</strong> erectile tissue<br />

that extends outside the body from the base <strong>of</strong> the<br />

pelvis. Ligaments attach the root <strong>of</strong> the penis (segment<br />

within the body) to the pubic bone at the

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