09.05.2017 Views

Encyclopedia of Health and Medicine

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

42 The Ear, Nose, Mouth <strong>and</strong> Throat<br />

OTOTOXIC MEDICATIONS<br />

Medications Commonly Prescribed to Treat Ototoxic Effects<br />

ANGIOTENSIN-CONVERTING ENZYME HYPERTENSION TINNITUS, HEARING LOSS<br />

(ACE) inhibitors: enalapril,<br />

usually temporary, reversible when<br />

lisinopril, ramipril, quinapril,<br />

medication stopped<br />

tr<strong>and</strong>olapril<br />

aminoglycoside antibiotics: in intravenous form: hearing loss, balance disturbances<br />

amikacin, gentamicin, kantamycin, Acinetobacter, Enterobacter, Pseudomonas, some degree <strong>of</strong> loss is <strong>of</strong>ten<br />

neomycin, streptomycin. <strong>and</strong> Mycobacter infections permanent; risk increases when also<br />

tobramycin in topical form: ear drops following taking any other medications with<br />

myringotomy<br />

ototoxic effects<br />

aspirin (salicylic acid) PAIN, INFLAMMATION, mild anticoagulant tinnitus, hearing loss with high doses,<br />

balance disturbances<br />

usually temporary, reversible when<br />

medication stopped<br />

platinum-derived CHEMOTHERAPY certain cancers (BLADDER, LUNG, ovarian moderate to severe hearing loss<br />

agents: carboplatin, cisplatin STOMACH, testicular) usually permanent<br />

loop diuretics: bumetanide, hypertension, congestive heart failure, tinnitus, hearing loss usually temporary,<br />

ethacrynic acid, furosemide, KIDNEY disease reversible when medication stopped<br />

torsemide<br />

macrolide antibiotics: Helicobacter pylori infection (PEPTIC hearing loss, sometimes severe<br />

azythromycin, clarithromycin, ULCER DISEASE), Legionella PNEUMONIA usually temporary, reversible when<br />

erythromycin (LEGIONNAIRES’ DISEASE), alternative when medication stopped<br />

when there are allergies to penicillin <strong>and</strong><br />

cephalosporin antibiotics<br />

NONSTEROIDAL ANTI-INFLAMMATORY pain, inflammation, arthritis tinnitus, mild to moderate hearing loss,<br />

DRUGS (NSAIDS):<br />

balance disturbances<br />

over the counter (OTC): ibupr<strong>of</strong>en,<br />

usually temporary, reversible when<br />

naproxen sodium, ketopr<strong>of</strong>en<br />

medication stopped<br />

prescription: oxaprozin, dicl<strong>of</strong>enic,<br />

etodolac, meloxicam, celecoxib,<br />

bismuth subsalicylate (for example, gastrointestinal upset, DIARRHEA tinnitus, mild to moderate hearing loss,<br />

Pepto-Bismol)<br />

balance disturbances<br />

usually temporary, reversible when<br />

medication stopped<br />

quinine, chloroquine, quinidine MALARIA, arrhythmias, leg cramps tinnitus, mild to moderate hearing loss,<br />

balance disturbances, vertigo<br />

usually temporary, reversible when<br />

medication stopped

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!