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Encyclopedia of Health and Medicine

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200 The Integumentary System<br />

ABCD SKIN EXAMINATION<br />

Characteristic Normal Suspicious<br />

A asymmetry matching halves (symmetrical) unequal or nonmatching halves (asymmetrical)<br />

B border smooth, even edges ragged, notched, or otherwise uneven edges<br />

C color single shade <strong>of</strong> brown varied shades <strong>of</strong> brown; multiple colors<br />

D diameter less than one quarter inch larger than one quarter inch<br />

for malignant melanoma. After doing several skin<br />

self-examinations, most people are familiar with<br />

their usual lesions <strong>and</strong> blemishes <strong>and</strong> can quickly<br />

identify any changes that have taken place since<br />

the previous self-exam. A dermatologist should<br />

evaluate any suspicious findings.<br />

See also ACTINIC KERATOSIS; LESION; SEBORRHEIC<br />

KERATOSIS.<br />

skin tag<br />

See ACROCHORDON.<br />

staphylococcal scalded skin syndrome A potentially<br />

life-threatening bacterial INFECTION <strong>of</strong> the<br />

skin that most commonly affects infants <strong>and</strong><br />

young children. Staphylococcus aureus is the infective<br />

agent. The infection is systemic, causing eruptions<br />

on the skin that give the appearance <strong>of</strong><br />

scalding. A single LESION heralds the onset <strong>of</strong> the<br />

infection, with multiple lesions rapidly emerging.<br />

The lesions are scarlet red <strong>and</strong> quickly BLISTER. The<br />

blisters (bullae) are very fragile <strong>and</strong> peel away<br />

from the skin with touch. The lesions spread to be<br />

contiguous with one another, covering large portions<br />

<strong>of</strong> the body. The loss <strong>of</strong> skin exposes the<br />

body to other pathogens that can cause complicating<br />

infections <strong>and</strong> means the body cannot maintain<br />

proper thermal or fluid regulation. Prompt<br />

diagnosis <strong>and</strong> treatment with ANTIBIOTIC MEDICA-<br />

TIONS is essential. Most children fully recover with<br />

appropriate treatment. The infection is highly contagious.<br />

Diligent HAND WASHING is crucial for caregivers<br />

<strong>and</strong> family members.<br />

See also BACTERIA; BULLA; PATHOGEN; TOXIC EPIDER-<br />

MAL NECROLYSIS; TOXIC SHOCK SYNDROME.<br />

Stevens-Johnson syndrome<br />

NECROLYSIS.<br />

See TOXIC EPIDERMAL<br />

stretch marks Irregular, discolored streaks or<br />

lines in the SKIN. Stretch marks represent, as the<br />

name suggests, changes in the tissue structure <strong>and</strong><br />

appearance that result from the skin stretching<br />

<strong>and</strong> separating from the underlying supportive tissues.<br />

Such stretching most commonly occurs with<br />

PREGNANCY, BREAST augmentation surgery, <strong>and</strong><br />

weight gain <strong>and</strong> loss, <strong>and</strong> affects the abdomen,<br />

upper arms, thighs, <strong>and</strong> breasts. Early stretch<br />

marks appear pink; mature stretch marks are generally<br />

pale. In addition to the altered pigmentation,<br />

stretch marks may have a different texture<br />

than the surrounding skin. Stretch marks are cosmetic<br />

<strong>and</strong> do not affect health or reflect health<br />

conditions. Cosmetic treatments to minimize the<br />

appearance <strong>of</strong> stretch marks include laser therapy<br />

<strong>and</strong> topical products such as glycolic lotions <strong>and</strong><br />

tretinoin cream.<br />

See also PLASTIC SURGERY.<br />

sunburn Damage to the epidermis <strong>and</strong> sometimes<br />

the dermis, the top <strong>and</strong> middle layers <strong>of</strong> the<br />

SKIN, as a consequence <strong>of</strong> extended, unprotected<br />

sun exposure. The sun emits several wavelengths<br />

<strong>of</strong> ultraviolet light. Those that reach the earth’s<br />

surface are ultraviolet A (UVA) <strong>and</strong> ultraviolet B<br />

(UVB). Each affects the skin in different ways.<br />

UVA activates melanocytes, the cells that produce<br />

melanin (pigment) <strong>and</strong> may produce a thermal<br />

(heat) response that causes the skin to turn red.<br />

Though the skin may feel hot, this is not actually<br />

sunburn but rather a thermal (heat) response.<br />

Sunburn is a delayed response to UVB exposure.<br />

UVB lightwaves do not activate the<br />

melanocytes but instead affect keratinocytes.<br />

When the epidermis (skin’s outer layer) contains<br />

deeply pigmented keratinocytes, such as in a person<br />

who has dark skin or a tan from previous sun<br />

exposure, the pigment (melanin) absorbs the UVB<br />

<strong>and</strong> the keratinocytes escape damage. When the<br />

skin is light, melanin distribution is also light <strong>and</strong><br />

there is little absorption <strong>of</strong> UVB.

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