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Encyclopedia of Health and Medicine

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270 Surgery<br />

Surgical Operation<br />

THORACOTOMY<br />

tonsillectomy<br />

Purpose<br />

operations on structures within the chest except the HEART<br />

remove chronically infected <strong>and</strong> enlarged tonsils<br />

TRACHEOSTOMY<br />

create a passage from the TRACHEA through the surface <strong>of</strong> the neck<br />

TYMPANOPLASTY<br />

repair or reconstruction <strong>of</strong> the TYMPANIC MEMBRANE (eardrum)<br />

VASECTOMY<br />

remove a segment <strong>of</strong> the VAS DEFERENS<br />

surgery, many people now use the terms operation<br />

<strong>and</strong> surgery interchangeably.<br />

See also ARTHROSCOPY; BARIATRIC SURGERY; CARDIAC<br />

CATHETERIZATION; CATARACT EXTRACTION AND LENS<br />

REPLACEMENT; CESAREAN SECTION; ENDOSCOPY; JOINT<br />

REPLACEMENT; LASER SURGERY; MINIMALLY INVASIVE SUR-<br />

GERY; MOHS’ SURGERY; PLASTIC SURGERY; REFRACTIVE<br />

SURGERY; SURGERY BENEFIT AND RISK ASSESSMENT; TUBAL<br />

LIGATION.<br />

organ transplantation The surgical replacement<br />

<strong>of</strong> a nonfunctioning vital organ with a functional<br />

organ acquired from a donor. Most donor organs<br />

are allogeneic, also called deceased donation or<br />

cadaver donation, in which a specialized surgical<br />

team removes the donated organs after a person’s<br />

death when the person has previously authorized,<br />

or when the person’s family authorizes at the time<br />

<strong>of</strong> the person’s death, organ donation. In some circumstances<br />

a person may make a living organ<br />

donation to another person, such as for kidney,<br />

lung lobe, <strong>and</strong> partial LIVER. US surgeons perform<br />

almost 27,000 organ transplantations each year,<br />

nearly 7,000 <strong>of</strong> which are organs from living<br />

donors. The most commonly transplanted organs<br />

are KIDNEYS <strong>and</strong> livers. However, approximately<br />

89,000 people remain on waiting lists for donor<br />

organs.<br />

TRANSPLANTED ORGANS AND TISSUES<br />

BONE MARROW CORNEA HEART<br />

ISLETS OF LANGERHANS cells kidney LIVER<br />

lung PANCREAS SKIN<br />

SMALL INTESTINE<br />

stem cells<br />

Organ Allocation <strong>and</strong> Acquisition<br />

Organ transplantation transitioned from experimental<br />

to mainstream in the 1980s, riding a wave<br />

<strong>of</strong> technologic advances <strong>and</strong> the success <strong>of</strong><br />

cyclosporine, the first effective immunosuppressive<br />

DRUG. In 1984 the US Congress passed the<br />

National Organ Transplant Act (NOTA), which<br />

established the Organ Procurement <strong>and</strong> Transplantation<br />

Network (OPTN) to ensure consistency<br />

<strong>and</strong> equity in the allocation <strong>of</strong> deceased donor<br />

organs. OPTN is a not-for-pr<strong>of</strong>it organization that<br />

is a collaborative union <strong>of</strong> public <strong>and</strong> private<br />

organizations. The United Network for Organ<br />

Sharing (UNOS) administers OPTN under contract<br />

to the US Department <strong>of</strong> <strong>Health</strong> <strong>and</strong> Human Services.<br />

Hospital transplant programs across the<br />

United States determine a person’s eligibility for<br />

transplantation, then submit the person’s name<br />

<strong>and</strong> health data (such as organ needed <strong>and</strong> blood<br />

type) to the UNOS database.<br />

A regional organ procurement organization<br />

(OPO) receives notification from hospitals <strong>and</strong><br />

other health-care providers when deceased donor<br />

organs become available within its geographic<br />

boundaries. The OPO coordinates the effort to<br />

match the organs with appropriate donors, initiating<br />

a “match run” from the UNOS database. The<br />

match run identifies prospective transplant recipients<br />

waiting for the particular kind <strong>of</strong> organ, the<br />

medical urgency <strong>of</strong> the transplant need, the general<br />

health circumstances, <strong>and</strong> the geographic<br />

proximity <strong>of</strong> the donor organ to the prospective<br />

recipient. The matched names go on a list for<br />

the organ, ranked in order <strong>of</strong> need. UNOS generates<br />

a new match run each time an organ becomes

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