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Encyclopedia of Health and Medicine

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feverfew 67<br />

with NONSTEROIDAL ANTI-INFLAMMATORY DRUGS<br />

(NSAIDS), causing stomach upset, irritation, <strong>and</strong><br />

bleeding. Because dong quai affects blood flow, it<br />

may also alter the intended effects <strong>of</strong> anticoagulant<br />

medications. And because <strong>of</strong> its actions to<br />

relax smooth muscle including the UTERUS, women<br />

should not take dong quai when they are pregnant.<br />

DONG QUAI (Angelica sinensis)<br />

Uses Risks/Side Effects Interactions<br />

menstrual cramps excessive bleeding anticoagulants<br />

menopausal stomach irritation NSAIDS<br />

discomforts<br />

ENDOMETRIOSIS<br />

See also BLACK<br />

COHOSH; DYSMENORRHEA; MENO-<br />

PAUSE; MENSTRUATION; PREMENSTRUAL SYNDROME; SOY.<br />

echinacea An herb with immune-supportive<br />

properties. Echinacea remedies incorporate stems,<br />

leaves, <strong>and</strong> seeds or their extracts from three <strong>of</strong><br />

the nine species <strong>of</strong> echinacea (Echinacea angustifolia,<br />

E. pallida, E. purpurea). Though herbalists typically<br />

use certain <strong>of</strong> the species according to the<br />

desired immune effect, commercially produced<br />

echinacea products typically contain a mix. The<br />

most common use <strong>of</strong> echinacea is to lessen the<br />

severity <strong>of</strong> COLDS, INFLUENZA, <strong>and</strong> other upper respiratory<br />

infections. Echinacea seems most effective<br />

when taken at the first indication <strong>of</strong> symptoms<br />

<strong>and</strong> can shorten the length <strong>of</strong> illness by 20 to 60<br />

percent.<br />

Echinacea seems less effective in protecting<br />

against upper respiratory infections when taken as<br />

a general prophylactic measure, though regular<br />

use may prevent canker sores. <strong>Health</strong> experts caution<br />

people to take echinacea for no longer than<br />

three weeks to give their immune systems a break<br />

from the echinacea’s stimulation <strong>and</strong> to wait one<br />

week before taking another course <strong>of</strong> echinacea.<br />

Some herbalists recommend using echinacea in<br />

rotation with other immune-boosting herbs. There<br />

is no clinical evidence to support a role for echinacea<br />

in preventing infections such as HIV/AIDS or<br />

HEPATITIS. Though echinacea may additionally support<br />

the IMMUNE SYSTEM when taken in conjunction<br />

with ANTIBIOTIC MEDICATIONS to treat bacterial infections,<br />

it cannot replace antibiotics.<br />

Some studies have shown echinacea to have<br />

adverse effects in people who are IMMUNOCOMPRO-<br />

MISED, although this finding has been inconsistent.<br />

Doctors generally recommend against echinacea<br />

for people who have chronic immune system disorders<br />

such as RHEUMATOID ARTHRITIS, MULTIPLE SCLE-<br />

ROSIS, <strong>and</strong> SYSTEMIC LUPUS ERYTHEMATOSUS (SLE),<br />

because echinacea can overstimulate the immune<br />

system <strong>and</strong> make symptoms worse. Some people<br />

who have CHRONIC FATIGUE SYNDROME have experienced<br />

improvement with echinacea <strong>and</strong> other<br />

immune-enhancing herbs, however. People who<br />

have immune system disorders should discuss<br />

echinacea with their regular doctors before taking<br />

echinacea. Echinacea is available as a dietary supplement<br />

in the United States. People who are<br />

allergic to plants in the daisy (Aster) family may<br />

also be allergic to echinacea.<br />

ECHINACEA (E. angustifolia, E. pallida, E. purpurea)<br />

Uses Risks/Side Effects Interactions<br />

prevent COLDS <strong>and</strong> none known none known<br />

INFLUENZAnone<br />

reduce cold/flu duration<br />

general IMMUNE SYSTEM<br />

support<br />

See also CANKER SORE; GOLDENSEAL; INFECTION.<br />

feverfew An herb once popular for, as its name<br />

implies, lowering FEVER. However, current use<br />

focuses on its ability to prevent migraine<br />

headaches from developing <strong>and</strong> to minimize the<br />

symptoms <strong>of</strong> migraines when they do occur. The<br />

primary active ingredients researchers have isolated<br />

in feverfew (Tanacetum parthenium) are<br />

parthenolides, a group <strong>of</strong> mild prostagl<strong>and</strong>in suppressants.<br />

PROSTAGLANDINS are chemicals the body<br />

releases that are associated with PAIN. Aspirin <strong>and</strong><br />

other NONSTEROIDAL ANTI-INFLAMMATORY DRUGS<br />

(NSAIDS)<br />

achieve much <strong>of</strong> their pain-relieving<br />

effects through prostagl<strong>and</strong>in suppression.<br />

Prostagl<strong>and</strong>ins also are factors in the inflammatory<br />

processes associated with fever.<br />

The form <strong>of</strong> feverfew that appears most effective<br />

in preventing migraine headaches is the<br />

freeze-dried herb. However, the level <strong>of</strong> parthenolides<br />

in feverfew plants varies widely. Capsules<br />

<strong>and</strong> tablets appear to have little or no effect for

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