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Encyclopedia of Health and Medicine

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ain tumor 235<br />

apparent for weeks to months after the bleeding.<br />

Some people have significant permanent consequences<br />

such as PARALYSIS, SEIZURE DISORDERS, <strong>and</strong><br />

cognitive dysfunction. Many people who recover<br />

have minimal permanent consequences, particularly<br />

when diagnosis <strong>and</strong> treatment are immediate.<br />

PHYSICAL THERAPY, OCCUPATIONAL THERAPY, <strong>and</strong><br />

speech therapy help restore maximum function.<br />

Risk Factors <strong>and</strong> Preventive Measures<br />

Trauma to the head, such as may occur in MOTOR<br />

VEHICLE ACCIDENTS or falls, is the most common<br />

cause <strong>of</strong> brain hemorrhage. Proper restraints (seat<br />

belts <strong>and</strong> car seats) <strong>and</strong> helmets worn during<br />

activities such as bicycle riding <strong>and</strong> downhill skiing,<br />

help reduce the risk for head injury. Young<br />

children <strong>and</strong> elderly adults are at highest risk for<br />

head injury due to falls. HYPERTENSION (high BLOOD<br />

PRESSURE) is the most significant preventable risk<br />

factor for intracerebral hemorrhage (bleeding<br />

within the tissues <strong>of</strong> the brain). Lifestyle factors<br />

such as cigarette smoking, which causes changes<br />

in the structure <strong>of</strong> the walls <strong>of</strong> the arteries, <strong>and</strong><br />

lack <strong>of</strong> regular physical activity can exacerbate the<br />

effects <strong>of</strong> hypertension. People who take anticoagulant<br />

medications (“blood thinners”) or who consume<br />

excessive amounts <strong>of</strong> ALCOHOL have<br />

increased risk for brain hemorrhage because these<br />

substances slow the blood’s ability to clot. People<br />

who have MARFAN SYNDROME also have increased<br />

risk for brain hemorrhage as this congenital disorder<br />

causes abnormalities in the blood vessel structures.<br />

See also COGNITIVE FUNCTION AND DYSFUNCTION;<br />

CONCUSSION; TRAUMATIC BRAIN INJURY (TBI).<br />

brain tumor An abnormal growth that arises<br />

within the tissues <strong>of</strong> the BRAIN. Brain tumors may<br />

be noncancerous or cancerous, <strong>and</strong> cancerous<br />

brain tumors may be primary (originate in the<br />

brain) or metastatic (spread to the brain from cancer<br />

that originates elsewhere in the body). About<br />

75 percent <strong>of</strong> cancerous brain tumors are metastatic.<br />

Primary brain cancer very seldom spreads<br />

beyond the CENTRAL NERVOUS SYSTEM (brain <strong>and</strong><br />

SPINAL CORD). In general noncancerous brain<br />

tumors are easier to treat than primary cancerous<br />

brain tumors because they tend to remain contained.<br />

However, the tumor’s size <strong>and</strong> location are<br />

<strong>of</strong>ten the more relevant factors in determining<br />

treatment options <strong>and</strong> prognosis (prospects for<br />

recovery). Because the cranium, which houses the<br />

brain, is a closed space, any extra mass within it<br />

puts pressure on the tissues <strong>of</strong> the brain that can<br />

cause serious damage or death. Though all <strong>of</strong> the<br />

brain is important, some areas are vital to sustain<br />

the functions <strong>of</strong> life. A tumor growing in such an<br />

area, such as the brainstem, may become lifethreatening<br />

more quickly than a tumor growing<br />

elsewhere in the brain. As well, some areas <strong>of</strong> the<br />

brain, again such as the brainstem, are inoperable—that<br />

is, a neurosurgeon cannot get to the<br />

tumor to remove it. Neurologists grade (classify)<br />

brain tumors according to their cells <strong>of</strong> origin, size,<br />

likelihood to grow in size, <strong>and</strong> likelihood to infiltrate<br />

(spread into) the tissues <strong>and</strong> supportive<br />

structures <strong>of</strong> the brain. Many brain tumors contain<br />

a combination <strong>of</strong> cell types.<br />

TYPES OF BRAIN TUMORS<br />

astrocytoma<br />

chordoma<br />

craniopharyngioma dermoid cyst<br />

ependymoma<br />

epidermoid cyst<br />

ganglioglioma<br />

ganglioneuroma<br />

glioblastoma<br />

glioblastoma multiforme (GBM)<br />

glioma<br />

hemangioblastoma<br />

medulloblastoma (MDL) meningioma<br />

neuroglioma<br />

oligodendroglioma<br />

pineal germinoma pituitary ADENOMA<br />

primary malignant primitive neuroectodermal tumor<br />

lymphoma<br />

(PNET)<br />

Symptoms <strong>and</strong> Diagnostic Path<br />

The symptoms <strong>of</strong> a brain tumor depend on the<br />

tumor’s location <strong>and</strong> the parts <strong>of</strong> the brain the<br />

tumor’s presence affects. Though HEADACHE can be<br />

among the symptoms <strong>of</strong> brain tumor, most<br />

headaches, even those that are severe, do not indicate<br />

a brain tumor. Disturbances <strong>of</strong> balance, motor<br />

control (movement <strong>and</strong> coordination), special<br />

senses (sight, smell, taste, <strong>and</strong> hearing), cognitive<br />

function, memory, <strong>and</strong> emotions are common<br />

general symptoms <strong>of</strong> brain tumors. Brain tumors<br />

may also cause seizures, NAUSEA <strong>and</strong> VOMITING, <strong>and</strong><br />

weakness or PARALYSIS on one side <strong>of</strong> the body.<br />

The diagnostic path begins with a PERSONAL<br />

HEALTH HISTORY <strong>and</strong> NEUROLOGIC EXAMINATION, with

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