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Encyclopedia of Health and Medicine

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cholesterol blood levels The amounts <strong>and</strong> forms<br />

<strong>of</strong> cholesterol that are present in the bloodstream,<br />

usually measured after 8 to 12 hours <strong>of</strong> fasting (no<br />

food) to accommodate short-term rises that could<br />

result from eating. Cholesterol is a sterol, a chemical<br />

essential for numerous metabolic functions<br />

<strong>and</strong> necessary for health. Because cholesterol cannot<br />

dissolve in the BLOOD, it binds with protein<br />

carriers called lipoproteins that suspend it in the<br />

blood. Cholesterol becomes a health problem<br />

when the amount <strong>of</strong> cholesterol in the blood circholesterol<br />

blood levels 35<br />

occlude the inner channel <strong>of</strong> the carotid artery.<br />

Carotid bruit is a diagnostic sign that indicates the<br />

presence <strong>of</strong> CAROTID STENOSIS (narrowing <strong>of</strong> the<br />

carotid artery) <strong>and</strong> increased risk for STROKE.<br />

See also ANGIOGRAM; ENDARTERECTOMY; HEART<br />

SOUNDS; STENT.<br />

carotid stenosis Narrowing <strong>of</strong> the carotid ARTERY<br />

in the neck due to ATHEROSCLEROSIS. Often carotid<br />

stenosis shows no symptoms until it results in a<br />

STROKE. The doctor may detect carotid stenosis<br />

during routine physical examination when listening<br />

to the carotid arteries with a STETHOSCOPE,<br />

which reveals the characteristic murmur sound,<br />

CAROTID BRUIT, that indicates the stenosis. ANTICO-<br />

AGULATION THERAPY, most commonly ASPIRIN<br />

THERAPY, helps reduce the risk <strong>of</strong> clot formation at<br />

the site <strong>of</strong> the stenosis though does not prevent or<br />

reduce atherosclerotic accumulations. ENDARTEREC-<br />

TOMY, surgery to remove the occluding atheromas<br />

(collections <strong>of</strong> ATHEROSCLEROTIC PLAQUE) <strong>and</strong> widen<br />

the arterial passage, becomes a viable treatment<br />

option when the stenosis reaches 60 or 70 percent.<br />

ANGIOGRAM, in which the cardiologist uses<br />

dye <strong>and</strong> X-rays to examine the arteries, helps<br />

define the degree <strong>of</strong> occlusion. Stroke occurs<br />

when clot or atheroma fragments break free from<br />

the site <strong>of</strong> the stenosis <strong>and</strong> travel through the<br />

carotid artery to the BRAIN.<br />

See also CARDIOVASCULAR DISEASE PREVENTION; SUR-<br />

GERY BENEFIT AND RISK ASSESSMENT.<br />

chest pain Discomfort that arises from the upper<br />

portion <strong>of</strong> the body. CHEST PAIN can have various<br />

causes, many <strong>of</strong> which are not cardiovascular. Discomfort<br />

originating from the HEART is characteristically<br />

oppressive in nature, though <strong>of</strong>ten not the<br />

crushing pressure that is the common perception.<br />

As many as 25 percent <strong>of</strong> people do not experience<br />

appreciable pain with HEART ATTACK. Gastrointestinal<br />

pain <strong>of</strong>ten sends people to the emergency<br />

room worried about heart attack, yet nearly a<br />

third <strong>of</strong> people who are having heart attacks delay<br />

seeking medical care because they do not believe<br />

the symptoms they are experiencing, especially<br />

chest pain, are severe enough to be heart attack.<br />

Chest pain is unreliable as an indicator <strong>of</strong> the<br />

nature or severity <strong>of</strong> a health situation.<br />

HEALTH CONDITIONS THAT CAN CAUSE CHEST PAIN<br />

BARRETT’S ESOPHAGUS<br />

dissecting aortic ANEURYSM<br />

GALLBLADDER DISEASE<br />

HEPATIC ABSCESS<br />

LUNG ABSCESS<br />

PANCREATITIS<br />

PERICARDITIS<br />

PLEURISY<br />

PULMONARY EMBOLISM with<br />

infarction<br />

COSTOCHONDRITIS<br />

ENDOCARDITIS<br />

GASTROESOPHAGEAL REFLUX<br />

DISORDER (GERD)<br />

HIATAL HERNIA<br />

MYOCARDITIS<br />

PEPTIC ULCER DISEASE<br />

PNEUMONIA<br />

rib FRACTURES<br />

STOMACH CANCER<br />

See also CARDIOPULMONARY RESUSCITATION (CPR);<br />

CHONDRITIS; COCAINE.<br />

CHOLESTEROL BLOOD LEVELS AND CARDIOVASCULAR HEALTH<br />

Cholesterol Optimal Moderate Risk High Risk<br />

HDL-C > – 60 mg/dL < 40 mg/dL not applicable<br />

LDL-C < – 100 mg/dL* 130–159 mg/dL* >160 mg/dL<br />

total cholesterol < 200 mg/dL 200–239 mg/dL > – 240 mg/dL<br />

*For people with no other cardiovascular risk factors, LDL-C levels <strong>of</strong> 100–129 mg/dL is optimal. For people with other cardiovascular<br />

risk factors, LDL-C levels <strong>of</strong> 100–129 mg/dL is nearly optimal/slight risk.

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