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Encyclopedia of Health and Medicine

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interstitial lung disorders 205<br />

tion, the decrease triggers actions in the body<br />

designed to slow the breathing. Key among these<br />

is temporary loss <strong>of</strong> consciousness (fainting),<br />

which returns breathing to the involuntary control<br />

<strong>of</strong> the brainstem <strong>and</strong> restores normal breathing<br />

patterns. People who are hyperventilating<br />

<strong>of</strong>ten feel as if they were not getting enough oxygen,<br />

though in fact they are getting plenty. Most<br />

<strong>of</strong>ten hyperventilation results from emotional<br />

stress, panic, or anxiety. Rarely, cardiovascular or<br />

pulmonary disturbances cause a similar breathing<br />

pattern. Chest X-RAY, blood tests, <strong>and</strong> ELECTROCAR-<br />

DIOGRAM (ECG) can quickly determine whether this<br />

is the case.<br />

The st<strong>and</strong>ard treatment for an active episode <strong>of</strong><br />

hyperventilation is breathing slowly <strong>and</strong> purposefully.<br />

Breathing through only one nostril (holding<br />

the other nostril closed with the fingers) helps<br />

focus conscious intent on the breathing as well as<br />

reduce the amount <strong>of</strong> air entering the LUNGS.<br />

Though once a common remedy for<br />

hyperventilation, BREATHING into a<br />

paper bag may allow carbon dioxide<br />

levels in the blood to rise too much.<br />

Doctors no longer recommend this<br />

method.<br />

Once breathing returns to normal the<br />

oxygen–carbon dioxide balance in the blood does<br />

the same <strong>and</strong> symptoms such as dizziness or lightheadedness<br />

fade. Stress management methods<br />

such as MEDITATION <strong>and</strong> YOGA help lower overall<br />

anxiety levels, which reduces hyperventilation<br />

episodes. BREATHING EXERCISES are also helpful.<br />

Hyperventilation without underlying cardiovascular<br />

or pulmonary disease is not harmful to health.<br />

See also HYPOXIA.<br />

hypoxemia<br />

See OXYGEN SATURATION.<br />

hypoxia Inadequate oxygen perfusion <strong>of</strong> the tissues.<br />

Hypoxia occurs when the BLOOD cannot<br />

deliver adequate oxygen, which may result from<br />

pulmonary dysfunction, cardiovascular dysfunction,<br />

STROKE, TRAUMATIC BRAIN INJURY (TBI), disorders<br />

<strong>of</strong> the blood such as ANEMIA that affect erythrocytes<br />

(red blood cells) or HEMOGLOBIN, <strong>and</strong> BREATH-<br />

ING disturbances such as APNEA. Hypoxia may<br />

involve only a defined organ or area, such as a<br />

region <strong>of</strong> the BRAIN affected by STROKE, or involve<br />

the entire body. Permanent tissue damage or tissue<br />

death results when hypoxia persists. Symptoms<br />

<strong>of</strong> hypoxia may include CYANOSIS (bluish hue<br />

to the lips <strong>and</strong> SKIN), tiredness, <strong>and</strong> DYSPNEA (shortness<br />

<strong>of</strong> breath or difficulty breathing). Most<br />

hypoxia requires supplemental oxygen with additional<br />

treatment that targets the underlying cause.<br />

See also ALTITUDE SICKNESS; DECOMPRESSION SICK-<br />

NESS; OXYGEN SATURATION; OXYGEN THERAPY; POLY-<br />

CYTHEMIA VERA.<br />

interstitial lung disorders A broad term for<br />

chronic conditions that restrict the ability <strong>of</strong> the<br />

LUNGS to function properly, encompassing more<br />

than 150 diseases. Interstitial lung disorders, also<br />

called interstitial lung disease as a collective term,<br />

are typically obstructive, fibrotic (involve SCAR formation),<br />

<strong>and</strong> progressive. Many arise from<br />

occupational exposures such as to asbestos<br />

(ASBESTOSIS), silica (SILICOSIS), <strong>and</strong> coal dust<br />

(miner’s PNEUMONOCONIOSIS). A variant form that<br />

more commonly occurs later in life, idiopathic<br />

pulmonary fibrosis (IPF), has no identifiable cause<br />

<strong>and</strong> tends to be more severe in its progression.<br />

The general symptoms, diagnostic paths, <strong>and</strong><br />

treatment approaches are similar for interstitial<br />

lung disorders. Common symptoms include<br />

COUGH, DYSPNEA (shortness <strong>of</strong> breath or difficulty<br />

BREATHING), <strong>and</strong> frequent INFECTION. Treatment targets<br />

slowing the progression <strong>of</strong> the disease, relieving<br />

symptoms, <strong>and</strong> preventing infections. Lung<br />

transplantation is sometimes a treatment option<br />

for severely progressive IPF. However, many people<br />

who have interstitial lung disorders are able to<br />

manage their symptoms for years to decades,<br />

allowing satisfactory QUALITY OF LIFE.<br />

See also CHRONIC OBSTRUCTIVE PULMONARY DISEASE<br />

(COPD); CYSTIC FIBROSIS AND THE LUNGS; LIVING WITH<br />

CHRONIC PULMONARY CONDITIONS.

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