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Encyclopedia of Health and Medicine

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164 The Integumentary System<br />

Outlook <strong>and</strong> Lifestyle Modifications<br />

For the first few weeks following surgery the scalp<br />

is swollen <strong>and</strong> tender, <strong>and</strong> the replacement sites<br />

may bleed with strenuous physical activity. Surgeons<br />

recommend refraining from intense exercise<br />

or activity <strong>and</strong> contact sports for two or three<br />

weeks after the procedure. The scalp remains tender<br />

(though the swelling subsides within a few<br />

weeks) for up to three or four months, depending<br />

on the replacement method. Transplanted hair<br />

growth does not look exactly the same as the hair<br />

that previously grew from the transplant site,<br />

though most people experience satisfactory results<br />

when a qualified <strong>and</strong> experienced cosmetic surgeon<br />

performs the surgery. It generally takes a<br />

year or two from the final hair replacement procedure<br />

to see the full effects.<br />

There must be abundant healthy hair on the<br />

back <strong>and</strong> sides <strong>of</strong> the head to serve as donor hair.<br />

Men in whom male pattern hair loss begins early<br />

in life are more likely to experience severe or total<br />

hair loss as they age. Satisfactory results from hair<br />

replacement surgery are less certain when this is<br />

the case, as the transplanted follicles may also<br />

experience hair loss. Hair loss from follicles native<br />

to the site generally continues, particularly in<br />

male pattern hair loss, which can result in irregular<br />

growth patterns <strong>and</strong> the need for further hair<br />

replacement.<br />

See also ANALGESIC MEDICATIONS; PLASTIC SURGERY;<br />

SURGERY BENEFIT AND RISK ASSESSMENT.<br />

hidradenitis suppurativa A condition <strong>of</strong> chronic<br />

INFLAMMATION resulting from blockage <strong>of</strong> the HAIR<br />

follicles (follicular occlusion). The inflammation<br />

may involve the apocrine gl<strong>and</strong>s, SWEAT GLANDS<br />

that secrete fluid into the hair follicles. The hair<br />

follicles then channel the sweat to the surface <strong>of</strong><br />

the SKIN. When sebum or cellular debris plugs the<br />

apocrine gl<strong>and</strong>’s opening, fluid backs up into the<br />

gl<strong>and</strong>. The situation results in an INFECTION that<br />

produces a hard, painful, reddened NODULE below<br />

the skin’s surface. Though the nodules will heal in<br />

three or four weeks without treatment, they <strong>of</strong>ten<br />

SCAR <strong>and</strong> recur. Treatment with oral ANTIBIOTIC<br />

MEDICATIONS may help control the condition<br />

though does not always clear it up. Occasionally<br />

the dermatologist needs to lance (surgically open)<br />

the nodule to allow it to drain. Dermatologists do<br />

not know what causes hidradenitis suppurativa to<br />

develop, though it is more common in people who<br />

have OBESITY.<br />

See also ABSCESS; CELLULITIS; FOLLICULITIS.<br />

hives<br />

See URTICARIA.<br />

hyperhidrosis Excessive sweating that results<br />

from abnormal functioning <strong>of</strong> the nerves or BLOOD<br />

vessels that supply the eccrine SWEAT GLANDS.<br />

Hyperhidrosis characteristically involves the h<strong>and</strong>s<br />

(palms), feet (soles), <strong>and</strong> axillae (underarms),<br />

though can affect eccrine sweat gl<strong>and</strong>s anywhere<br />

in the body. The eccrine sweat gl<strong>and</strong>s produce<br />

most <strong>of</strong> the body’s sweat <strong>and</strong> play a key role in<br />

thermoregulation (regulating body heat). They<br />

empty their fluids (perspiration) directly to the<br />

SKIN’s surface for rapid evaporation <strong>and</strong> cooling.<br />

Stress <strong>and</strong> physical activity tend to exacerbate<br />

hyperhidrosis, particularly when it affects primarily<br />

the h<strong>and</strong>s <strong>and</strong> feet. The portion <strong>of</strong> the BRAIN<br />

that regulates sweating in these areas, the cerebral<br />

cortex, is not part <strong>of</strong> the body’s thermoregulation<br />

system but rather responds to emotional signals<br />

such as anxiety <strong>and</strong> fear. Hyperhidrosis may also<br />

occur as an undesired SIDE EFFECT <strong>of</strong> medications<br />

or a symptom <strong>of</strong> metabolic disorders such as<br />

HYPERTHYROIDISM <strong>and</strong> DIABETES, or health conditions<br />

such as TUBERCULOSIS <strong>and</strong> Hodgkin’s LYMPHOMA.<br />

Most hyperhidrosis that arises from structural or<br />

functional anomalies <strong>of</strong> the nerves or blood vessels<br />

first appears in ADOLESCENCE, when the hormonal<br />

changes <strong>of</strong> PUBERTY stimulate sweat gl<strong>and</strong><br />

function. Hyperhidrosis that begins later in life<br />

generally arises from underlying health conditions.<br />

Symptoms <strong>and</strong> Diagnostic Path<br />

The primary symptom <strong>of</strong> hyperhidrosis is pr<strong>of</strong>usely<br />

excessive sweating. The h<strong>and</strong>s <strong>and</strong> feet,<br />

when involved, may be continually wet. Sweating<br />

from the underarms <strong>and</strong> other areas <strong>of</strong> the body<br />

typically drenches clothing, requiring frequent<br />

clothing changes. The diagnostic path typically<br />

includes a comprehensive NEUROLOGIC EXAMINATION<br />

<strong>and</strong> blood tests to measure HORMONE levels. The<br />

doctor may conduct further diagnostic procedures,<br />

depending on the individual’s health circumstances.

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