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Encyclopedia of Health and Medicine

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418 Appendix VIII<br />

realign themselves. The MRI machine then detects<br />

the rate at which the nuclei return to their natural<br />

alignment. A computer constructs multidimensional<br />

images based on this data.<br />

MRI is particularly effective for detecting abnormal<br />

tissue within the body, such as tumors, tears to<br />

muscles, <strong>and</strong> neurologic injury or deterioration.<br />

Because <strong>of</strong> the electromagnetic disruption the MRI<br />

machine temporarily causes, people who have<br />

implanted pacemakers <strong>and</strong> other devices, metal<br />

hardware (such as to repair fractures), permanent<br />

prostheses (such as an artificial eye or COCHLEAR<br />

IMPLANT), <strong>and</strong> certain other circumstances cannot<br />

undergo MRI. It is essential to remove all clothing<br />

<strong>and</strong> items that may contain metal; the person wears<br />

a hospital gown during the procedure.<br />

MRI is painless <strong>and</strong> takes 15 minutes to an hour<br />

depending on the area <strong>of</strong> the body being scanned.<br />

Sometimes the doctor may choose to administer an<br />

intravenous injection <strong>of</strong> a contrast medium to<br />

enhance the images the MRI produces. The MRI<br />

machine is very loud <strong>and</strong> surrounds the person<br />

during the procedure. Some people find the experience<br />

<strong>of</strong> the procedure disconcerting because <strong>of</strong><br />

these factors. The technologist performing the MRI<br />

can provide methods to minimize this. MRI does<br />

not have any adverse side effects.<br />

radionuclide scan A nuclear medicine procedure<br />

that measures the rate <strong>of</strong> deterioration <strong>of</strong><br />

low-level radioactive isotopes to present images <strong>of</strong><br />

the cellular function <strong>of</strong> organs such as the BRAIN,<br />

BONE, LIVER, THYROID<br />

GLAND, <strong>and</strong> GALLBLADDER.<br />

Radionuclide scans involve exposure to radiation.<br />

Before the scan, the person receives an intravenous<br />

injection <strong>of</strong> a small amount <strong>of</strong> fluid, typically<br />

a glucose (sugar) solution, “tagged” with the<br />

appropriate radioisotope (the radionuclide). Cells<br />

throughout the body uptake, or take in, the<br />

tagged glucose molecules. The attached radioisotope<br />

molecules deteriorate as the body uses the<br />

glucose.<br />

Cells in various organs <strong>and</strong> structures use glucose<br />

at known rates; measuring the rate helps<br />

doctors to determine whether there is abnormal<br />

function such as tumors or healing (increased glucose<br />

use). Slowed uptake may indicate degenerative<br />

disorders or problems with healing.<br />

During the scan the person lies on a procedure<br />

table <strong>and</strong> the gamma camera or other device passes<br />

over the area <strong>of</strong> the body being evaluated. The procedure<br />

may take 15 to 90 minutes. There is usually<br />

no need to change out <strong>of</strong> regular clothes. The risks<br />

<strong>of</strong> radionuclide scans are minimal. The radioisotopes<br />

dissipate rapidly, so the radiation does not<br />

remain in the body very long. Specialized types <strong>of</strong><br />

radionuclide scans include positron emission<br />

tomography (PET) scan <strong>and</strong> single photon emission<br />

computed tomography (SPECT).<br />

ultrasound Also called ultrasonography, a<br />

diagnostic procedure that uses high-frequency<br />

sound waves (beyond the frequency human hearing<br />

can detect) to create images <strong>of</strong> internal organs<br />

<strong>and</strong> structures. Ultrasound does not involve exposure<br />

to radiation. Ultrasound is painless <strong>and</strong> is<br />

especially effective for evaluating hollow structures<br />

within the body such as the GALLBLADDER,<br />

urinary BLADDER, <strong>and</strong> arteries <strong>and</strong> veins. Doppler<br />

ultrasound is a technique that presents moving<br />

images, such as the flow <strong>of</strong> BLOOD or the movement<br />

<strong>of</strong> a FETUS within a pregnant woman’s<br />

uterus. Ultrasound is also useful for detecting cysts<br />

<strong>and</strong> tumors in structures such as the OVARIES, TESTI-<br />

CLES, BREASTS, <strong>and</strong> PROSTATE GLAND. Doctors sometimes<br />

use ultrasound to guide the placement <strong>of</strong><br />

biopsy instruments.<br />

Ultrasound typically requires no advance<br />

preparation, though pelvic ultrasound may<br />

require a full urinary bladder. The procedure is<br />

painless. During the procedure, the sonographer<br />

applies a warm gel to the surface <strong>of</strong> the skin over<br />

the area being scanned. The gel improves the conductivity<br />

<strong>of</strong> sound signals. The sonographer gently<br />

presses a transducer against the skin <strong>and</strong> moves it<br />

in a particular pattern. The transducer emits ultrasound<br />

waves, which “echo” from the structures<br />

within the body. The transducer then picks up the<br />

echoes <strong>and</strong> transmits them back to the ultrasound<br />

machine, which creates representational images<br />

from them.<br />

Some ultrasound procedures involve placing<br />

the transducer within a natural body opening<br />

such as the VAGINA, RECTUM, or ESOPHAGUS to provide<br />

focused examination <strong>of</strong> key structures that<br />

are deeper within the body. Transesophageal<br />

ultrasound, for example, can provide close examination<br />

<strong>of</strong> the heart. ECHOCARDIOGRAM is another<br />

type <strong>of</strong> ultrasound that specifically examines the<br />

HEART.

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