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Encyclopedia of Health and Medicine

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salivary gl<strong>and</strong>s Structures within the MOUTH that<br />

produce saliva, a watery fluid that mixes with<br />

food during chewing <strong>and</strong> maintains the mouth as<br />

a moist environment. The major salivary gl<strong>and</strong>s<br />

are primarily along the floor <strong>of</strong> the mouth (the<br />

sublingual <strong>and</strong> subm<strong>and</strong>ibular gl<strong>and</strong>s) <strong>and</strong> at<br />

the back <strong>of</strong> the mouth just below the EAR<br />

(parotid gl<strong>and</strong>s). These gl<strong>and</strong>s produce a steady<br />

supply <strong>of</strong> saliva that trickles into the mouth to<br />

moisturize mucous membranes. Stimuli related to<br />

eating, such as the smell or appearance <strong>of</strong> food,<br />

activate an increased flow <strong>of</strong> saliva to meet the<br />

needs <strong>of</strong> mastication (chewing). Enzymes in saliva<br />

begin to break down foods to prepare them for<br />

digestion.<br />

The facial <strong>and</strong> glossopharyngeal nerves, the<br />

seventh <strong>and</strong> ninth CRANIAL NERVES respectively,<br />

regulate the functions <strong>of</strong> the salivary gl<strong>and</strong>s. The<br />

glossopharyngeal NERVE also h<strong>and</strong>les nerve<br />

impulses for the sense <strong>of</strong> taste. Small mineral calculi,<br />

or stones, can block the salivary ducts that<br />

drain saliva from the salivary gl<strong>and</strong>s, causing PAIN<br />

<strong>and</strong> swelling (SIALOLITHIASIS). Excessive saliva (SIAL-<br />

ORRHEA), or drooling, can a symptom <strong>of</strong> various<br />

neurologic conditions, including CEREBRAL PALSY<br />

<strong>and</strong> PARKINSON’S DISEASE, <strong>and</strong> <strong>of</strong>ten accompanies<br />

SWALLOWING DISORDERS. Saliva production temporarily<br />

increases in young children who are<br />

teething, likely an attempt by the body to soothe<br />

the discomfort <strong>of</strong> the new TEETH erupting through<br />

the surface <strong>of</strong> the gums. The parotid gl<strong>and</strong>s swell<br />

with the MUMPS.<br />

For further discussion <strong>of</strong> the salivary gl<strong>and</strong>s<br />

within the context <strong>of</strong> otolaryngologic structure<br />

<strong>and</strong> function please see the overview section “The<br />

Ear, Nose, Throat, <strong>and</strong> Mouth.”<br />

See also SIALADENITIS.<br />

septal deviation A shift from midline in the<br />

nasal septum (wall <strong>of</strong> tissue that separates the air<br />

pathways <strong>of</strong> the NOSE). Septal deviation can cause<br />

various health conditions such as chronic SINUSITIS<br />

(INFECTION), EPISTAXIS (nosebleed), <strong>and</strong> obstructed<br />

BREATHING. It can occur as a natural defect or result<br />

from trauma such as a blow to the nose. The treatment<br />

<strong>of</strong> choice is surgical correction (septoplasty)<br />

to restore the septum to midline. Septal deviation<br />

<strong>of</strong>ten accompanies structural anomalies <strong>of</strong> the<br />

nose that cause people to seek RHINOPLASTY (surgical<br />

reconstruction <strong>of</strong> the nose).<br />

See also SEPTAL PERFORATION; SURGERY BENEFIT AND<br />

RISK ASSESSMENT.<br />

septal perforation An abnormal opening in the<br />

nasal septum (wall <strong>of</strong> tissue within the NOSE that<br />

divides the nostrils), that occurs as the result <strong>of</strong><br />

chronic irritation, trauma, or cancer. Septal perforation<br />

may develop with long-term use <strong>of</strong> nasal<br />

oxygen, long-term use <strong>of</strong> corticosteroid nasal<br />

sprays (such as to treat ALLERGIC RHINITIS), inhalation<br />

<strong>of</strong> illicit drugs such as COCAINE or aerosols <strong>and</strong><br />

glues, foreign objects in the nose, chronic digital<br />

trauma (picking the nose), or long-term exposure<br />

to chromates such as chromic acid <strong>and</strong> chromium<br />

(used in electroplating <strong>and</strong> other industrial applications).<br />

Septal perforation sometimes occurs as a<br />

consequence <strong>of</strong> RHINOPLASTY, particularly when<br />

there have been several operations.<br />

Symptoms <strong>of</strong> septal perforation may include a<br />

whistling sound when BREATHING, nasal discharge,<br />

<strong>and</strong> bleeding (EPISTAXIS). The preferred treatment<br />

for most septal perforations is surgical repair (septoplasty),<br />

though it is sometimes necessary to first<br />

remedy the underlying cause. The doctor may<br />

place a nasal septal prosthesis, commonly called a<br />

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