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Encyclopedia of Health and Medicine

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food allergies 261<br />

Symptoms <strong>and</strong> Diagnostic Path<br />

A hypersensitivity reaction to a food produces<br />

symptoms that may include<br />

• itching <strong>and</strong> swelling around the face, on the<br />

lips, <strong>and</strong> in the MOUTH<br />

• nasal congestion<br />

• wheezing or difficulty BREATHING<br />

• sensation <strong>of</strong> a lump in the THROAT<br />

• gastrointestinal PAIN (resulting from swelling in<br />

the intestinal mucosa)<br />

• moderate to extensive diarrhea<br />

More generalized symptoms such as SKIN rash,<br />

hives (URTICARIA), <strong>and</strong> ANGIOEDEMA are also possible.<br />

Symptoms may occur within minutes to 2<br />

hours after eating the food. Anaphylaxis may<br />

develop with any hypersensitivity reaction, even<br />

when previous reactions have been mild.<br />

ANAPHYLAXIS is a medical emergency<br />

that requires immediate treatment<br />

from a doctor. Tingling <strong>and</strong> swelling <strong>of</strong><br />

the lips, tongue, <strong>and</strong> THROAT 20 to 60<br />

minutes after eating a food for which<br />

there could be an allergy are possible<br />

indications <strong>of</strong> anaphylaxis.<br />

When there is a clear connection between a<br />

specific food <strong>and</strong> a hypersensitivity response,<br />

identifying the allergen is fairly straightforward.<br />

When the connection is not clear, the diagnostic<br />

path can be arduous <strong>and</strong> may include<br />

• blood tests to measure IMMUNOGLOBULIN E (IgE)<br />

levels<br />

• ALLERGY TESTING with suspect substances<br />

• elimination diet<br />

The elimination diet involves removing suspected<br />

foods or foods that are common allergens<br />

from the diet, usually for two weeks, <strong>and</strong> then<br />

reintroducing them one at a time until symptoms<br />

recur. The last food reintroduced is the likely<br />

allergen. An elimination diet is appropriate only<br />

for people who have mild to moderate hypersensitivity<br />

reactions. The risk for anaphylaxis is too<br />

great to use the elimination diet approach in people<br />

who have had severe allergy symptoms such<br />

as wheezing, breathing difficulty, or urticaria<br />

(hives). No single diagnostic approach works for<br />

all food allergies; diagnosis becomes a process <strong>of</strong><br />

drawing conclusions based on symptoms.<br />

COMMON FOOD ALLERGIES<br />

cow’s milk<br />

eggs<br />

peanuts<br />

shellfish (lobster, shrimp, crab)<br />

soy<br />

strawberries<br />

tree nuts (almonds, wheat (including flour)<br />

cashews, walnuts, pecans)<br />

Treatment Options <strong>and</strong> Outlook<br />

A moderate hypersensitivity reaction may require<br />

treatment with ANTIHISTAMINE MEDICATIONS; a serious<br />

reaction may require a course <strong>of</strong> oral CORTI-<br />

COSTEROID MEDICATIONS to halt the immune<br />

response <strong>and</strong> relieve the discomfort <strong>of</strong> the symptoms.<br />

Many hypersensitivity reactions to foods<br />

produce mild symptoms that go away without<br />

treatment. A doctor should evaluate symptoms<br />

that do not improve within a few days.<br />

The most effective long-term treatment is to<br />

avoid the allergen. This is not always as easy as it<br />

sounds because <strong>of</strong>ten variations <strong>of</strong> the allergen are<br />

ingredients in prepared or baked foods. Peanuts,<br />

eggs, milk, soy, <strong>and</strong> wheat are common in many<br />

foods. Cross-contamination is also a concern, particularly<br />

among processed foods manufactured in<br />

facilities that use various ingredients in different<br />

products. An ice cream manufacturer may make a<br />

flavor that has nuts, for example, <strong>and</strong> then use the<br />

same equipment to make a flavor that does not<br />

have nuts. Even residue not visible to the eye can<br />

be sufficient to cause a hypersensitivity reaction in<br />

someone who is highly allergic. Labels on packaged<br />

foods include information about whether the<br />

product comes from a facility in which cross-contamination<br />

is possible. People who have food<br />

allergies must ask about obvious as well as hidden<br />

ingredients when eating away from home.<br />

DESENSITIZATION (allergy shots) is a therapeutic<br />

option for people who have allergies to foods that<br />

are especially common or who have severe hypersensitivity<br />

reactions. Though it takes up to two<br />

years for desensitization to reach its maximum<br />

effectiveness, most people notice a reduced hypersensitivity<br />

reaction within six months.

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