Encyclopedia of Health and Medicine

396 Cancer
Tumor Marker Corresponding Cancer Reliability
CA-72-4 OVARIAN CANCER; STOMACH CANCER; PANCREATIC unreliable for diagnosis
CANCER; COLORECTAL CANCER
CA-125 ovarian cancer unreliable for diagnosis
may be elevated in women who have
previously had cancer and are currently
cancer free
elevated in endometriosis and benign
OVARIAN CYST
CA-5-3 breast cancer unreliable for diagnosis in early stages;
moderate for diagnosis in metastatic
disease
effective for recurrence
elevation possible in women who do not
have cancer
CA-9-9 pancreatic cancer moderately reliable for diagnosis
CALCITONIN medullary THYROID CANCER effective for diagnosis
CARCINOEMBRYONIC ANTIGEN colorectal cancer; LUNG CANCER; breast cancer unreliable for diagnosis
(CEA)
effective for recurrence
elevated in numerous noncancerous
health conditions
elevated in people who smoke
chromogranin A neuroendocrine cancers moderate for diagnosis
HER-2/neu breast cancer unreliable for diagnosis
moderate for monitoring treatment
human chorionic gestational trophoblastic neoplasia (GTN); moderate for diagnosis
gonadotropin (hCG) TESTICULAR CANCER; ovarian cancer effective for monitoring treatment
M-protein multiple myeloma effective for diagnosis
effective for monitoring treatment
NEURON-specific enolase (NSE) small-cell lung cancer (SCLC) modest for diagnosis
moderate for monitoring treatment
PROSTATE-SPECIFIC ANTIGEN (PSA) prostate cancer effective for diagnosis
effective for monitoring treatment
elevated in BENIGN PROSTATIC HYPERPLASIA
(BPH)