workshop, held in May 2011, additional case studies illustrating advanced riskassessment methodologies were presented and the Expert Panel discussedoverarching considerations <strong>for</strong> problem <strong>for</strong>mulation, use of mode of action,and addressing background and endogenous exposures. Recognizing thatthere is wide variety of risk assessment applications, depending upon problem<strong>for</strong>mulation, the Expert Panel adopted a framework to organize examples ofmethodology applicable to different risk assessment needs, including qualitative,screening, and in-depth assessments. The case studies were linked tothese different risk assessment objectives to provide examples of the rangeof available methods; this is envisioned to be expanded to provide a compendiumof methods to illustrate specific dose-response techniques <strong>for</strong> differentrisk assessment settings. This symposium will present the results and recommendationsof this ARA project with specific focus on the Expert Panel’sdiscussions <strong>for</strong> improving problem <strong>for</strong>mulation and use of mode of action,the framework and compendium of dose-response methods, and specific casestudies centered on conveying the application of the framework <strong>for</strong> in<strong>for</strong>mingmethod selection.T3-I Symposium: Catastrophic Climate ChangeClimate change is among the most significant catastrophic risks that globalsociety faces. This session features a range of perspectives on catastrophic climatechange and responses to it. Scholarship a diverse range of fields includingeconomics, engineering, geography, and psychology bring insight to howsevere the threat of climate change is and how the threat can be addressedthrough measures including incentives, institutions, and geoenengineering.T4-B Panel Discussion: Symposium: Public Preferences and RegulatoryDecision-Making - Smart Imputs <strong>for</strong> Smart Decisions?As climate change becoming one of the most important issues facing humandevelopment, countries are trying to find suitable solutions to this nonreversibleprocedure. All over the world, low-carbon development options arewidely discussed and have started being adopted both at national and local level.As the basic unit of public service providing economic development as wellas ecological sustainability, various actors in society including governments,industry and civil society, take on responsibility <strong>for</strong> balancing environmentalprotection and economic development. In this process, the essential questionlies in how to make smart decisions on the basis of expertise, public valuesand citizen preferences. The key research question in the research presentedhere is to explore how these essential groups <strong>for</strong>m their own opinion on low-46carbon technologies selection <strong>for</strong> power supply, communicate these opinionsto others and how this selection may influence regulatory decision making.The symposium will be divided into two parts. First, three short presentationswill provide data and results from the US and Germany within a total of 45minutes. Second, a set of panelists (including Ortwin Renn, Ragnar Löfstedt)will discuss within a total of 45 minutes the issue of public preferences as apolicy factor. We would like to thank the Stiftung Mercator <strong>for</strong> financial support<strong>for</strong> doing this research.T4-C Symposium: Improving Problem Formulation and Dose-ResponseBeyond Science and Decision, Part 2Under the Alliance <strong>for</strong> <strong>Risk</strong> Assessment (ARA), a series of public workshopsled by an Expert Panel of toxicologists and risk assessors were heldin 2010 and 2011 to continue the discussion on elements of risk assessmentset <strong>for</strong>th by the 2009 NRC report “Science and Decisions: Advancement of<strong>Risk</strong> Assessment.” This ARA activity was supported by 45 entities, includinggovernment agencies, industry groups, scientific societies, non-profit organizations/consortia,and consulting groups. The first ARA workshop explored avariety of perspectives on issues raised by the NAS 2009 report and discussedpossible case studies to address these. Representative case studies were thendeveloped and evaluated during the second ARA workshop. In the third ARAworkshop, held in May 2011, additional case studies illustrating advanced riskassessment methodologies were presented and the Expert Panel discussedoverarching considerations <strong>for</strong> problem <strong>for</strong>mulation, use of mode of action,and addressing background and endogenous exposures. Recognizing thatthere is wide variety of risk assessment applications, depending upon problem<strong>for</strong>mulation, the Expert Panel adopted a framework to organize examples ofmethodology applicable to different risk assessment needs, including qualitative,screening, and in-depth assessments. The case studies were linked tothese different risk assessment objectives to provide examples of the rangeof available methods; this is envisioned to be expanded to provide a compendiumof methods to illustrate specific dose-response techniques <strong>for</strong> differentrisk assessment settings. This symposium will present the results and recommendationsof this ARA project with specific focus on the Expert Panel’sdiscussions <strong>for</strong> improving problem <strong>for</strong>mulation and use of mode of action,the framework and compendium of dose-response methods, and specific casestudies centered on conveying the application of the framework <strong>for</strong> in<strong>for</strong>mingmethod selection.
T4-E Symposium: Food Safety <strong>Risk</strong> Prioritization and Decision <strong>Analysis</strong>Increasing concerns regarding food safety in the U.S. has led to new legislationthat affects producers and suppliers at all levels of the supply chain andhelps increase protection <strong>for</strong> consumers. The Food Safety Modernization Act,signed into law on January 4, 2011, includes provisions to prevent, detect, andrespond to food safety problems. The law calls <strong>for</strong> a risk-based approach thatestablishes priorities, targets significant food safety risks, and minimizes foodborneillness, a strategy that was advocated in the 2010 report released by theInstitute of Medicine and National Research Council, Enhancing Food Safety:The Role of the Food and Drug Administration. Consequently, there is anurgent need <strong>for</strong> decision frameworks and associated methods/tools/data thatcan be used to (1) rank risks <strong>for</strong> food commodities and hazards; (2) establishpriorities based on public health impacts and other non-health related consequences;(3) compare the feasibility, efficacy, and cost effectiveness of variousmitigation options; and (4) develop an optimal strategy to allocate resources toreduce the burden of foodborne disease. This symposium will focus on ongoingand recent research into methods, models, and data that can be used tosupport science-based decision making, prioritizing hazard-commodity risksusing decision attributes relevant to public health outcomes and policy objectives.The symposium will provide an overview of a prototype decision supportsystem recently completed by the U.S. Food and Drug Administration,and highlight recent research in the risk ranking/prioritization methods thatis critical in the decision-making process. Key issues that will be addressedinclude the importance of developing quality data, the advantages and disadvantagesof “top down” versus “bottom up” approaches, and the integrationof risk-based metrics with non-risk metrics within a decision-making context.T4-I Symposium: Global Catastrophic <strong>Risk</strong>Global catastrophic risks (GCRs) are risks of events that could significantlyharm or even destroy civilization at the global scale. GCRs are thusrisks of the highest magnitude, regardless of probability. Major GCRs includeclimate change, pandemics, nuclear warfare, and potential new technologies.This symposium features diverse perspectives on how to effectively assess andrespond to GCRs through research, policy, and other means.WEDNESDAYW1-A Symposium: How the Public Responds to Different Disasters overTime: The Role of Perceived <strong>Risk</strong>, Emotion and <strong>Risk</strong> CommunicationTo understand the underlying dynamics of public response amidst a crisiswe need to observe how perceived risk, emotion, and risk-related behaviorsemerge and co-vary over time. Specifically, we must examine their trajectories,that is, how these factors escalate, peak and then decline. We also need toconsider their potential consequences, and the mitigating role of risk communication.This session will discuss findings from studies that include terrorism,technological accidents and natural disasters. Reports are drawn from casestudies, simulated scenarios and longitudinal surveys following actual events.Methodological challenges will be discussed. Recommendations <strong>for</strong> risk andcrisis communication will be offered.W1-B Symposium: Analytical Approaches to Food Safety ManagementThe USDA Food Safety and Inspection Service is exploring quantitativerisk assessment methodologies to incorporate the use of Codex Alimentarius’newly adopted risk management metrics. Traditionally, regulated food processingsystems have relied on process control and per<strong>for</strong>mance standards toachieve a safe and wholesome product. In the past, such measures have notbeen associated with public heath outcomes and there<strong>for</strong>e the impact not easilymeasured. However, the use of quantitative microbiological risk assessmenthas allowed linking of public health outcomes due to consumption with theproduct’s microbiological status at the processing establishment. To improvepublic health and the sanitary situation in member countries, the World TradeOrganization agreed to sanitary and phytosanitary measures including the AppropriateLevel of Protection (ALOP, risk of illness per serving), and the recentlyadopted risk management metrics Food Safety Objective (FSO, cfu/g atconsumption) and Per<strong>for</strong>mance Objectives (PO, cfu/g at designated controlpoints in the food process). By hypothesizing various levels of acceptable risk,risk assessment can be used to link these public health outcomes with bacteriallevels in food at the point of processing and ultimately establish the stringencyof a food safety process. However, the practical application of using risk assessment<strong>for</strong> this purpose and the development of the methodological toolshas only recently garnered attention. To meet the need to develop tools toestablish these new food safety metrics, two examples were developed: Listeriamonocytogenes in ready-to-eat (RTE) deli meats and Salmonella and Campylobacterin chicken. By modifying these risk assessments, we demonstrate47
- Page 4 and 5: Ballroom C1Monday10:30 AM-NoonM2-A
- Page 9 and 10: US Environmental Protection Agency
- Page 11 and 12: Workshops - Sunday, December 4Full
- Page 13 and 14: WK9: Eliciting Judgments to Inform
- Page 15 and 16: These freely available tools apply
- Page 17 and 18: Plenary SessionsAll Plenary Session
- Page 19 and 20: 10:30 AM-NoonRoom 8/9M2-F Panel Dis
- Page 21 and 22: 1:30-3:00 PMRoom 8/9M3-F Symposium:
- Page 23 and 24: 4:50 pm M4-E.5Modeling of landscape
- Page 25 and 26: P.35 Health risk assessment of meta
- Page 27 and 28: Works-In-ProgressP.99 Assessing the
- Page 29 and 30: 10:30 AM-NoonRoom 8/9T2-F Error in
- Page 31 and 32: 1:30-3:00 PMRoom 8/9T3-F AppliedMet
- Page 34 and 35: 8:30-10:00 AMBallroom C1W1-A Sympos
- Page 36 and 37: 10:30 AM-NoonBallroom C1W2-A Commun
- Page 38: 1:30-3:00 PMBallroom C1W3-A Communi
- Page 41 and 42: 3:30-4:30 PMRoom 8/9W4-F Environmen
- Page 43 and 44: oth recent advances, and ongoing ch
- Page 45 and 46: M3-H Symposium: Analyzing and Manag
- Page 47: Part 2, we consider the use of expe
- Page 51 and 52: While integral to guiding the devel
- Page 53 and 54: have contributed to past difficulti
- Page 55 and 56: M2-C.1 Abraham IM, Henry S; abraham
- Page 58 and 59: serious accident of the Tokyo Elect
- Page 60 and 61: een found that independence assumpt
- Page 62 and 63: W4-I.1 Beach RH, McCarl BA, Ohrel S
- Page 64 and 65: M4-A.1 Berube DM; dmberube@ncsu.edu
- Page 66 and 67: W4-A.1 Boerner FU, Jardine C, Dried
- Page 69 and 70: M2-G.1 Brink SA, Davidson RA; rdavi
- Page 71 and 72: M4-H.5 Buede DM, Ezell BC, Guikema
- Page 73 and 74: same scientists’ environmental he
- Page 75 and 76: periods of time. Successful adaptat
- Page 77 and 78: P.123 Charnley G, Melnikov F, Beck
- Page 79 and 80: derived from mouse and rat testes t
- Page 81 and 82: esources under any circumstance in
- Page 83 and 84: W4-B.3 Convertino M, Collier ZA, Va
- Page 85 and 86: addition, over 10% thought that eve
- Page 87 and 88: Reference Dose (RfD). The average e
- Page 89 and 90: W2-H.2 Demuth JL, Morss RE, Morrow
- Page 91 and 92: T4-H.4 Dingus CA, McMillan NJ, Born
- Page 93 and 94: methods research priorities and pot
- Page 95 and 96: W3-A.2 Eggers SL, Thorne SL, Sousa
- Page 97 and 98: tions) were < 1 for sub-populations
- Page 99 and 100:
sociated with model error. Second,
- Page 101 and 102:
inter-donation interval to mitigate
- Page 103 and 104:
Fukushima nuclear accident coverage
- Page 105 and 106:
for growth inhibitor use and retail
- Page 107 and 108:
W1-C.1 Goble R, Hattis D; rgoble@cl
- Page 109 and 110:
stakeholders. The utility of this m
- Page 111 and 112:
T2-E.4 Guidotti TL; tee.guidotti@gm
- Page 113 and 114:
M4-C.2 Haines DA, Murray JL, Donald
- Page 115 and 116:
providing normative information of
- Page 117 and 118:
then allow both systems to operate
- Page 119 and 120:
tious disease outbreaks. Several cl
- Page 121 and 122:
P.122 Hosseinali Mirza V, de Marcel
- Page 123 and 124:
W2-B.1 Isukapalli SS, Brinkerhoff C
- Page 125 and 126:
M3-G.3 Jardine CG, Driedger SM, Fur
- Page 127 and 128:
P.88 Johnson BB, Cuite C, Hallman W
- Page 129 and 130:
metrics to provide risk management
- Page 131 and 132:
M4-C.1 Koch HM, Angerer J; koch@ipa
- Page 133 and 134:
certainty factors) and comparative
- Page 135 and 136:
T3-D.4 LaRocca S, Guikema SD, Cole
- Page 137 and 138:
P.71 Lemus-Martinez C, Lemyre L, Pi
- Page 139 and 140:
of excretion, and the increased che
- Page 141 and 142:
M2-D.4 MacKenzie CA, Barker K; cmac
- Page 143 and 144:
isk appetite and optimal risk mitig
- Page 145 and 146:
ameters, and enabled a more robust
- Page 147 and 148:
over the nature and format of infor
- Page 149 and 150:
Analysis (PRA). Existing parametric
- Page 151 and 152:
explosion of a bomb in a building,
- Page 153 and 154:
T3-G.3 Nascarella MA; mnascarella@g
- Page 155 and 156:
corresponding slowdown in container
- Page 157 and 158:
ing the scope and usage of the cybe
- Page 159 and 160:
dose for a variety of exposure scen
- Page 161 and 162:
“nanofibers”) is relatively und
- Page 163 and 164:
ment (CEA), which provides both a f
- Page 165 and 166:
T3-D.2 Resurreccion JZ, Santos JR;
- Page 167 and 168:
shore wind turbines have yet been b
- Page 169 and 170:
T2-D.3 Rypinski AD, Cantral R; Arth
- Page 171 and 172:
time and temperature, determining t
- Page 173 and 174:
esponse to requests from the EC, th
- Page 175 and 176:
ers and inspectors. Analysis examin
- Page 177 and 178:
smoked salmon, and associated expos
- Page 179 and 180:
and 95th percentiles). Increasing t
- Page 181 and 182:
esponse relationship for B. anthrac
- Page 183 and 184:
variation on Day 0. Results showed
- Page 185 and 186:
sidered. The most significant resul
- Page 187 and 188:
lived in a apartment (not including
- Page 189 and 190:
W3-C.4 von Stackelberg KE; kvon@eri
- Page 191 and 192:
P.12 Waller RR, Dinis MF; rw@protec
- Page 193 and 194:
W2-B.6 Wang D, Collier Z, Mitchell-
- Page 195 and 196:
iomonitoring “equivalent” level
- Page 197 and 198:
T4-H.2 Winkel D, Good K, VonNiederh
- Page 199 and 200:
mation insufficiency, risk percepti
- Page 201 and 202:
choices. This work examines these s
- Page 203 and 204:
sults and possible intended or unin
- Page 205 and 206:
AAbadin HG.................... 36,
- Page 207 and 208:
Gray GM............................
- Page 209 and 210:
Peters E...........................
- Page 211 and 212:
SECOND FLOOR Floor MapConvention Ce