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Environmental Profiles of Chemical Flame-Retardant Alternatives for

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Terrestrial Organism Toxicity<br />

Acute Oral (OPPTS Harmonized Guideline 850.2100), Dietary (OPPTS Harmonized<br />

Guideline 850.2200; OECD Guideline 205), or Reproductive Toxicity (OPPTS Harmonized<br />

Guideline 850.2300; OECD Guideline 206) in Birds<br />

Conclusion:<br />

No available acute oral, dietary, and reproductive toxicity data.<br />

Basis <strong>for</strong> Conclusion:<br />

No acute oral, dietary, or reproductive toxicity studies in birds were located.<br />

Earthworm Subchronic Toxicity (OPPTS Harmonized Guideline 850.6200; OECD<br />

Guideline 207)<br />

Conclusion:<br />

The available earthworm subchronic toxicity data were judged inadequate to meet the endpoint.<br />

Basis <strong>for</strong> Conclusion:<br />

No earthworm subchronic toxicity studies were located. An acute (14-hour) LC 50 <strong>of</strong> 130 mg/kg<br />

soil and a NOEC <strong>of</strong> 100 mg/kg soil with the earthworm, Eisenia fetida (SafePharm, 1996), were<br />

reported in IPCS 1998. However, the study has also been reported to be a 14-day subchronic<br />

toxicity study (NICNAS, 2001). The study, or a study summary, was not available <strong>for</strong> an<br />

independent evaluation <strong>of</strong> the study and the results.<br />

3-39

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