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Environmental Profiles of Chemical Flame-Retardant Alternatives for

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Proprietary G: Triaryl phosphate, isopropylated<br />

Synonym:<br />

CAS<br />

MF<br />

MW<br />

SMILES<br />

<strong>Chemical</strong> Identity<br />

Many <strong>of</strong> the available health effects studies were conducted with commercial mixtures that<br />

commonly contained triphenyl phosphate as well as Proprietary G. The available in<strong>for</strong>mation<br />

regarding the composition <strong>of</strong> these mixtures is presented below, but the composition <strong>of</strong> the actual<br />

samples tested in the health effects studies usually was not reported.<br />

[Formulation 1] is reported to contain 60-100% Proprietary G and 15-40% triphenyl phosphate (Ref.<br />

24) and [Formulation 2] is reported to contain 60-100% Proprietary G and 4-7% triphenyl phosphate<br />

(Ref. 25).<br />

Major Components <strong>of</strong> [Formulation 3] and [Formulation 4] as reported in Ref. 34<br />

Component [Formulation 3] [Formulation 4]<br />

Total Proprietary G 49 61<br />

[<strong>Chemical</strong> 1] 8 11<br />

[<strong>Chemical</strong> 2] 6 7<br />

[<strong>Chemical</strong> 3] 2 5<br />

[<strong>Chemical</strong> 4] 21 27<br />

[<strong>Chemical</strong> 5] 12 11<br />

Triphenyl Phosphate 33 18<br />

ACUTE TOXICITY<br />

Human Health Endpoints<br />

Acute Oral Toxicity (OPPTS Harmonized Guideline 870.1100; OECD Guidelines 425, 420,<br />

423, 401)<br />

Conclusion:<br />

The available acute oral toxicity data were judged inadequate to meet the endpoint.<br />

10-4

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