27.12.2012 Views

Environmental Profiles of Chemical Flame-Retardant Alternatives for

Environmental Profiles of Chemical Flame-Retardant Alternatives for

Environmental Profiles of Chemical Flame-Retardant Alternatives for

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Bioconcentration<br />

<strong>Environmental</strong> Fate<br />

Fish:<br />

Conclusion: The bioconcentration factor has been adequately characterized.<br />

Basis <strong>for</strong> Conclusion: The two studies cited in the table below provide consistent in<strong>for</strong>mation<br />

<strong>for</strong> killifish under both static and flow-through conditions, over a variety <strong>of</strong> observation times,<br />

and with varying initial concentrations <strong>of</strong> test substance. The BCF was also measured in<br />

goldfish; the reported BCFs are independent <strong>of</strong> study length.<br />

Reference Species BCF<br />

Ref. 46 Killifish 113<br />

110<br />

77<br />

Exp.<br />

type<br />

Key Design Parameters<br />

Range<br />

(ppb)<br />

Static 1,000<br />

initial<br />

Study<br />

length T (/C)<br />

24 hours<br />

55 hours<br />

96 hours<br />

Comments<br />

25 Half-life <strong>for</strong> elimination<br />

<strong>of</strong> the test compound in<br />

water + fish = 31 hours.<br />

Ref. 46 Goldfish 5 Static 1,000 24 hours 25 Half-life <strong>for</strong> elimination<br />

3 initial 96 hours <strong>of</strong> the test compound in<br />

water + fish = 42 hours.<br />

Ref. 47 Killifish 46±5<br />

Daphnids: No data<br />

Green Algae: No data<br />

Oysters: No data<br />

Earthworms: No data<br />

32±4<br />

31±6<br />

59±16<br />

49±12<br />

Flowthrough<br />

(all)<br />

400<br />

300<br />

40<br />

40<br />

80<br />

3 days<br />

4 days<br />

6 days<br />

30 days<br />

32 days<br />

25 BCF is independent <strong>of</strong><br />

concentration; continuous<br />

(flow-through) results<br />

correlate to static results<br />

(Ref. 46).<br />

Fish Metabolism:<br />

Conclusion: The metabolism <strong>of</strong> Proprietary A in fish is not adequately characterized in the<br />

literature.<br />

Basis <strong>for</strong> Conclusion: The depuration rate is adequately described in killifish, however, the<br />

metabolite distribution is not addressed.<br />

4-44

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!