Environmental Profiles of Chemical Flame-Retardant Alternatives for

Chronic Toxicity to Freshwater and Marine Fish (OPPTS Harmonized Guideline
850.1400; OECD Guideline 210)
Conclusion:
No available chronic toxicity data for freshwater and marine fish.
Basis for Conclusion:
No chronic toxicity studies in freshwater and marine fish were located.
Chronic Toxicity to Freshwater Invertebrates (OPPTS Harmonized Guideline 850.1300;
OECD 211) and Chronic Toxicity to Marine/Estuarine Invertebrates (OPPTS Harmonized
Guideline 850.1350)
Conclusion:
No available chronic toxicity data for freshwater and marine/estuarine invertebrates.
Basis for Conclusion:
No chronic toxicity studies in freshwater and marine/estuarine invertebrates were located.
Algal Toxicity (OPPTS Harmonized Guideline 850.5400; OECD Guideline 201)
Conclusion:
The available algal toxicity data were judged inadequate to meet the endpoint.
Basis for Conclusion:
The available data are summarized in Table 4-3. The summary of a 96-hour algal toxicity study
(Unpublished study conducted in 1992, summarized in Ref. 4, 5) indicates that the study does
not meet the OPPTS Harmonized Guideline 850.5400. The pH and temperature of the test water
during the study were outside of the acceptable ranges for Selenastrum capricornutum, as per
Guideline 850.5400. Moreover, the two highest concentrations tested exceed the estimated
water solubility of Proprietary A (42 mg/L) and the concentrations tested were apparently not
verified analytically. Additional information, including test substance purity, hardness, DO,
TOC, TSS, exposure vessel size and head space, and measured chemical concentrations, were
not provided in the summary. Also, there is no evidence that positive controls were used in
order to establish that the algae were responding in the expected manner to a known chemical.
The deviations from the OPPTS Guideline indicate that the study is inadequate to satisfy the
algal toxicity endpoint. Another study indicates that Proprietary A at 10 mg/L had no effect on
growth or biomass of the algal species Scenedesmus subspicatus exposed for 72 hours
4-36