Bulletin 2010/45 - European Patent Office

(C07D) I.1(1)
(72) FUJII, Nobuhiro, Osaka-shi Osaka 532-8686,
JP
OGURO, Yuya, Tsukuba-shi Ibaraki 300-
4293, JP
SASAKI, Satoshi, Tsukuba-shi Ibaraki 300-
4293, JP
KONDO, Shigeru, Osaka-shi Osaka 532-
8686, JP
(74) Dossmann, Gérard, et al, Casalonga &
Partners Bayerstrasse 71-73, 80335
München, DE
(51) C07D 471/04 (11) 2 247 589 A1*
A61K 31/33 A61P 25/00
(25) En (26) En
(21) 08802728.9 (22) 01.10.2008
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MT NL
NO PL PT RO SE SI SK TR
AL BA MK RS
(86) EP 2008/008309 01.10.2008
(87) WO 2009/059666 2009/20 14.05.2009
(30) 05.11.2007 EP 07291325
(54) • 7-AZAINDOLDERIVATE ALS SELEKTIVE
INHIBITOREN VON 11-BETA-HYDROXYS-
TEROIDDEHYDROGENASE VOM TYP 1
• 7-AZAINDOLE DERIVATIVES AS SELEC-
TIVE 11-BETA-HYDROXYSTEROID DEHY-
DROGENASE TYPE 1 INHIBITORS
• DÉRIVÉS 7-AZAINDOLE SERVANT D'INHI-
BITEURS SÉLECTIFS DE LA 11-BÉTA-
HYDROXYSTÉROÏDE DÉSHYDROGÉNASE
DE TYPE 1
(71) Merck Patent GmbH, Frankfurter Strasse
250, 64293 Darmstadt, DE
(72) CARNIATO, Denis, F-91460 Marcoussis, FR
SCHULTZ, Melanie, 64287 Darmstadt, DE
ROCHE, Didier, 69130 Ecully, FR
HALLAKOU-BOZEC, Sophie, F-92120 Montrouge,
FR
C07D 471/04 → (51) A61K 31/4985
C07D 471/04 → (51) C07D 403/12
(51) C07D 487/04 (11) 2 247 590 A1*
C07D 519/00 A61K 31/519
A61P 25/00 A61P 35/00
(25) En (26) En
(21) 09706486.9 (22) 30.01.2009
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MK MT
NL NO PL PT RO SE SI SK TR
AL BA RS
(86) EP 2009/000616 30.01.2009
(87) WO 2009/095254 2009/32 06.08.2009
(30) 01.02.2008 EP 08250396
01.02.2008 US 63421
(54) • PYRAZOLOPYRIMIDINE, EIN VERFAHREN
ZU IHRER HERSTELLUNG UND IHRE
VERWENDUNG ALS MEDIZIN
• PYRAZOLOPYRIMIDINES, A PROCESS
FOR THEIR PREPARATION AND THEIR
USE AS MEDICINE
• PYRAZOLOPYRIMIDINES, LEUR
MÉTHODE DE PRÉPARATION ET LEUR
UTILISATION COMME MÉDICAMENTS
(71) Merz Pharma GmbH & Co. KGaA, Eckenheimer
Landstrasse 100, 60318 Frankfurt am
Main, DE
(72) HENRICH, Markus, 35516 Muenzenberg, DE
WEIL, Tanja, Singapore 098627, SG
MÜLLER, Sibylle, 55263 Wackernheim, DE
NAGEL, Jens, D-14959 Blankensee, DE
GRAVIUS, Andreas, 97846 Partenstein, DE
KAUSS, Valerjans, LV-1082 Riga, LV
ZEMRIBO, Ronalds, LV-2008 Jurmala, LV
ERDMANE, Elina, LV-1019 Riga, LV
Europäisches Patentblatt
European Patent Bulletin
Bulletin européen des brevets
(74) Goddard, Christopher Robert, Dehns St
Bride's House 10 Salisbury Square, London
EC4Y 8JD, GB
(51) C07D 487/04 (11) 2 247 591 A1*
A61K 31/519
(25) En (26) En
(21) 09708802.5 (22) 04.02.2009
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MK MT
NL NO PL PT RO SE SI SK TR
AL BA RS
(86) EP 2009/051281 04.02.2009
(87) WO 2009/098236 2009/33 13.08.2009
(30) 06.02.2008 EP 08151137
(54) • PYRROLO [2,3-D] PYRIDINE UND DEREN
VERWENDUNG ALS TYROSIN KINASE
INHIBITOREN
• PYRROLO [2, 3-D]PYRIDINES AND USE
THEREOF AS TYROSINE KINASE INHIBI-
TORS
• PYRROLO [2,3-D]PYRIDINES ET LEUR
UTILISATION COMME INHIBITEURS DE
TYROSIN KINASE
(71) Novartis AG, Lichtstrasse 35, 4056 Basel, CH
(72) GAUL, Christoph, CH-4002 Basel, CH
GERSPACHER, Marc, CH-4002 Basel, CH
HOLZER, Philipp, CH-4002 Basel, CH
PISSOT SOLDERMANN, Carole, CH-4002
Basel, CH
(74) Dyer, James, Novartis Pharma AG Patent
Department, 4002 Basel, CH
(51) C07D 487/04 (11) 2 247 592 A1*
C07D 519/00 A61P 29/00
A61K 31/5025
(25) En (26) En
(21) 09713736.8 (22) 16.02.2009
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MK MT
NL NO PL PT RO SE SI SK TR
AL BA RS
(86) EP 2009/051757 16.02.2009
(87) WO 2009/106442 2009/36 03.09.2009
(30) 25.02.2008 US 31035
22.01.2009 US 205724
(54) • PYRROLOTRIAZIN-KINASEHEMMER
• PYRROLOPYRAZINE KINASE INHIBITORS
• INHIBITEURS DE LA PYRROLOPYRAZINE
KINASE
(71) F. Hoffmann-La Roche AG, Grenzacherstrasse
124, 4070 Basel, CH
(72) BAMBERG, Joe Timothy, East Palo Alto CA
94303, US
BARTLETT, Mark, Mountain View California
94040, US
DU BOIS, Daisy Joe, Palo Alto California
94304, US
ELWORTHY, Todd Richard, Los Altos California
94022, US
HENDRICKS, Robert Than, San Carlos California
94070, US
HERMANN, Johannes Cornelius, San Francisco
California 94107, US
KONDRU, Rama K., Sunnyvale California
94086, US
LEMOINE, Remy, San Francisco California
94114, US
LOU, Yan, San Jose California 95130, US
OWENS, Timothy D., Mountain View California
94040, US
PARK, Jaehyeon, Sunnyvale California
94087, US
SMITH, David Bernard, San Mateo California
94403, US
SOTH, Michael, Milpitas California 95035, US
YANG, Hanbiao, Sunnyvale California 94087,
US
74
Anmeldungen
Applications
Demandes (45/2010) 10.11.2010
YEE, Calvin Wesley, Daly City California
94015, US
(74) Heiroth, Ulrike Hildegard, F. Hoffmann-La
Roche AG Patent Department, 4070 Basel,
CH
(51) C07D 487/04 (11) 2 247 593 A1*
A61P 29/00 A61K 31/5025
(25) En (26) En
(21) 09714560.1 (22) 16.02.2009
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MK MT
NL NO PL PT RO SE SI SK TR
AL BA RS
(86) EP 2009/051759 16.02.2009
(87) WO 2009/106444 2009/36 03.09.2009
(30) 25.02.2008 US 31035 P
22.01.2009 US 146514 P
(54) • PYRROLOPYRAZIN-KINASEHEMMER
• PYRROLOPYRAZINE KINASE INHIBITORS
• INHIBITEURS DE KINASE PYRROLOPY-
RAZINE
(71) F. Hoffmann-La Roche AG, Grenzacherstrasse
124, 4070 Basel, CH
(72) DU BOIS, Daisy, Joe, Palo Alto California
94304, US
ELWORTHY, Todd, Richard, Los Altos California
94022, US
HENDRICKS, Robert, Than, San Carlos
California 94070, US
HERMANN, Johannes, Cornelius, San Francisco
California 94107, US
KONDRU, Rama, K., Sunnyvale California
94086, US
LOU, Yan, San Jose California 95130, US
OWENS, Timothy, D., Mountain View California
94040, US
PARK, Jaehyeon, Sunnyvale California
94087, US
SMITH, David, Bernard, San Mateo California
94403, US
SOTH, Michael, Milpitas California 95035, US
(74) Heiroth, Ulrike Hildegard, F. Hoffmann-La
Roche AG Patent Department, Grenzacherstrasse
124, CH-4070 Basel, CH
(51) C07D 487/04 (11) 2 247 594 A1*
A61K 31/519 A61P 15/00
A61P 11/00 A61P 19/00
(25) En (26) En
(21) 09714992.6 (22) 25.02.2009
(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB
GR HR HU IE IS IT LI LT LU LV MC MK MT
NL NO PL PT RO SE SI SK TR
AL BA RS
(86) EP 2009/052198 25.02.2009
(87) WO 2009/106531 2009/36 03.09.2009
(30) 27.02.2008 EP 08102052
(54) • PYRROLOPYRIMIDINCARBOXAMIDE
• PYRROLOPYRIMIDINECARBOXAMIDES
• PYRROLOPYRIMIDINE CARBOXAMIDES
(71) Nycomed GmbH, Byk-Gulden-Strasse 2,
78467 Konstanz, DE
(72) STADLWIESER, Josef, 78465 Konstanz, DE
SCHMIDT, Beate, 78476 Allensbach, DE
BERNSMANN, Heiko, 60325 Frankfurt, DE
SUDAU, Alexander, 42799 Leichlingen, DE
DUNKERN, Torsten, 78269 Volkertshausen,
DE
MARX, Degenhard, 78345 Moos, DE
DIEFENBACH, Jörg, 78333 Stockach-winterspüren,
DE
(74) Mechnich, Oliver M.J., Nycomed GmbH
Postfach 10 03 10, 78406 Konstanz, DE
(51) C07D 487/04 (11) 2 247 595 A1*
C07D 519/00 A61P 29/00