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Introduction to Acoustics

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Medical<br />

21. Medical<br />

Acous<br />

<strong>Acoustics</strong><br />

Medical acoustics can be subdivided in<strong>to</strong> diagnostics<br />

and therapy. Diagnostics are further separated<br />

in<strong>to</strong> audi<strong>to</strong>ry and ultrasonic methods, and both<br />

employ low amplitudes. Therapy (excluding medical<br />

advice) uses ultrasound for heating, cooking,<br />

permeablizing, activating and fracturing tissues<br />

and structures within the body, usually at<br />

much higher amplitudes than in diagnostics. Because<br />

ultrasound is a wave, linear wave physics<br />

are generally applicable, but recently nonlinear<br />

effects have become more important, even in<br />

low-intensity diagnostic applications.<br />

This document is designed <strong>to</strong> provide the<br />

nonmedical acoustic scientist or engineer with<br />

some insights in<strong>to</strong> acoustic practices in medicine.<br />

Auscultation with a stethoscope is the most basic<br />

use of acoustics in medicine and is dependent<br />

on the fields of incompressible (circulation) and<br />

compressible (respiration) fluid mechanics and<br />

frictional mechanics. Detailed discussions of<br />

tribology, laminar and turbulent hemodynamics,<br />

subsonic and supersonic compressional flow, and<br />

surfactants and inflation dynamics are beyond<br />

the scope of this document. However, some of<br />

the basic concepts of auscultation are presented<br />

as a starting point for the study of natural body<br />

sounds. Ultrasonic engineers have dedicated over<br />

half a century of effort <strong>to</strong> the development of<br />

ultrasound beam patterns and beam scanning<br />

methods, stretching the current technical and<br />

economic limits of analog and digital electronics<br />

and signal processing at each stage. The depth of<br />

these efforts cannot be covered in these few pages.<br />

However, the basic progression of progress in the<br />

fields of transducers and signal processing will be<br />

covered. The study of the interaction of ultrasound<br />

with living tissues is complicated by complex<br />

ana<strong>to</strong>mic structures, the high density of scatterers,<br />

and the constantly changing nature of the tissues<br />

with ongoing life processes including cardiac<br />

pulsations, the formation of edema and intrinsic<br />

noise sources. A great deal of work remains <strong>to</strong> be<br />

done on the ultrasonic characterization of tissues.<br />

Finally, the effect of ultrasound<br />

on tissues, both inadvertent and therapeutic will<br />

be discussed.<br />

Much of the medical acoustic literature<br />

published since 1987 is searchable online, so this<br />

document has included key words that will be<br />

helpful in performing a search. However, much<br />

of the important basic work was done before<br />

1987. In an attempt <strong>to</strong> help the reader <strong>to</strong> access<br />

that literature, Denis White and associates have<br />

compiled a complete bibliography of the medical<br />

ultrasound literature prior <strong>to</strong> 1987. Under Further<br />

Reading in this chapter, the reader will find a link<br />

<strong>to</strong> a complete compilation of 99 citations from<br />

Ultrasound in Medicine and Biology which list the<br />

thousands of articles on medical acoustics written<br />

prior <strong>to</strong> 1987.<br />

The academically based authors develop,<br />

use and commercialize diagnostic ultrasonic<br />

Doppler systems for the benefit of patients with<br />

cardiovascular diseases. To translate ultrasonic<br />

and acoustic innovation in<strong>to</strong> widespread clinical<br />

application requires as much knowledge about the<br />

economics of medicine, the training and practices<br />

of medical personnel, and the pathology and<br />

prevalence of diseases as about the diffraction<br />

patterns of ultrasound beams and signal-<strong>to</strong>-noise<br />

ratio of an echo. Although a discussion of these<br />

fac<strong>to</strong>rs is beyond the scope of this chapter, a few<br />

comments will help <strong>to</strong> provide perspective on the<br />

likely future contribution of medical acoustics <strong>to</strong><br />

improved public health.<br />

21.1 <strong>Introduction</strong> <strong>to</strong> Medical <strong>Acoustics</strong>.......... 841<br />

21.2 Medical Diagnosis; Physical Examination 842<br />

21.2.1 Auscultation – Listening<br />

for Sounds................................ 842<br />

21.2.2 Phonation and Auscultation ....... 847<br />

21.2.3 Percussion................................ 847<br />

21.3 Basic Physics of Ultrasound Propagation<br />

in Tissue ............................................. 848<br />

21.3.1 Reflection<br />

of Normal-Angle-Incident<br />

Ultrasound ............................... 850<br />

839<br />

Part F 21

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