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Introduction to Acoustics

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λ1 = c1 / fus<br />

θ1<br />

λ2 = c2 / fus<br />

λ1 / sin θ1 = λ2 / sin θ2<br />

θ2<br />

θ1<br />

c1 / sin θ1 = c2 / sin θ2<br />

Fig. 21.9 Refraction of ultrasound as it passes from one<br />

material <strong>to</strong> another. Dark brown: incident compressional<br />

wavefronts and wave vec<strong>to</strong>r incident at angle θ1. Light<br />

brown: reflected compressional wavefronts and wave vec<strong>to</strong>r<br />

reflecting at angle θ1. Gray: transmitted compressional<br />

wave. The interfacial shear wave increases in intensity as<br />

the ultrasound beam cross section coherently contributes<br />

<strong>to</strong> the wave; attenuation of the shear wave causes a rapid<br />

decrease in amplitude outside the beam<br />

the interface. This capillary wave is subject <strong>to</strong> high attenuation.<br />

Because tissue has an interface on every cell<br />

boundary and every tissue boundary, this mechanism is<br />

responsible for some of the conversion of incident ultrasound<br />

power in<strong>to</strong> heat as ultrasound propagates in<strong>to</strong><br />

tissue. It is important <strong>to</strong> notice that the propagation speed<br />

of the capillary wave is not the same as that of the component<br />

of the compressional wave directed along the<br />

interface, so the capillary wave is out of phase with the<br />

ultrasound wave, contributing <strong>to</strong> the transfer of energy<br />

in<strong>to</strong> the capillary wave. Outside the ultrasound beam,<br />

the capillary wave takes on its conventional wavelength<br />

(cs/ f ), where f is the ultrasound frequency. The propagation<br />

speed of the capillary wave (cs) is proportional<br />

<strong>to</strong> the interfacial tension.<br />

21.3.3 Diagnostic Ultrasound Propagation<br />

in Tissue<br />

Diagnostic ultrasound uses ultrasound frequencies of<br />

1–30MHz. (MHz = cycles per µs). The speed of ultrasound<br />

in most tissues is near 1.5mm/µs (1500 m/s).<br />

There are some notable exceptions. In bone the speed is<br />

between 3.5mm/µsand4mm/µs, and in air the speed is<br />

0.3mm/µs. In cartilage the speed is 1.75 mm/µswhich<br />

of course varies with composition. In fat the speed is<br />

Medical <strong>Acoustics</strong> 21.3 Basic Physics of Ultrasound Propagation in Tissue 851<br />

1.45 mm/µs(Table21.3). In muscle, the speed of ultrasound<br />

varies by about 1.5%, depending on the angle of<br />

propagation <strong>to</strong> fiber orientation.<br />

Although most authors focus attention on ultrasound<br />

frequency, ultrasound wavelength may be more convenient<br />

for understanding the important issues. There are<br />

three issues of importance:<br />

• Ultrasound cannot resolve structures smaller than<br />

the wavelength.<br />

• Scattering and attenuation [21.42] both depend on<br />

ultrasound wavelength and its relationship <strong>to</strong> the size<br />

of the scatterers.<br />

• The focusing properties of ultrasound beam patterns<br />

and the formation of side-lobes depend on the ratio<br />

between the wavelength and the width of the<br />

transducer.<br />

21.3.4 Amplitude of Ultrasound Echoes<br />

Red blood cells (erythrocytes) are 0.007 mm in diameter<br />

and about 0.001 mm thick. The largest cells in the<br />

body, nerve axons, may be 1 m long, but their diameter is<br />

about 0.001 mm. A liver cell is about 0.04 mm in diameter.<br />

The smallest structures imaged by ultrasound in<br />

clinical practice are layers less than 1 mm thick, such<br />

as the media lining major arteries (the intima-media<br />

thickness, IMT) [21.43], corneal layers (with 30 MHz<br />

ultrasound) and skin surfaces. However, these structures<br />

can only be observed in the range (depth) direction<br />

because resolution is best in that direction. Lateral resolution<br />

is dependent on the numeric aperture of the<br />

ultrasound beam pattern and the relationship between<br />

the object of interest and the focus as well as the ultrasound<br />

wavelength. Only the ultrasound wavelength<br />

affects depth resolution. The result is that ultrasound<br />

images are anisotropic, with much better resolution in<br />

the depth direction than in the lateral direction. The image<br />

is delivered <strong>to</strong> the examiner as a pic<strong>to</strong>rial map in<br />

two dimensions. In our optical experience, resolution is<br />

equal in the two dimensions. Therefore, we expect that,<br />

if we can see detail in one dimension, we can also see the<br />

detail in the other, even when we cannot. This gives the<br />

impression that ultrasound has higher resolving power<br />

in the lateral direction than it in fact does. This is particularly<br />

important in measurements such as the IMT and<br />

measuring the thickness of the atherosclerotic cap. Such<br />

structures can only be visualized when the ultrasound<br />

beam is oriented perpendicular <strong>to</strong> the structure.<br />

To identify tissues and organs, the lateral dimensions<br />

must by at least 10 wavelengths wide. This<br />

Part F 21.3

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