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Introduction to Acoustics

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852 Part F Biological and Medical <strong>Acoustics</strong><br />

Part F 21.3<br />

Table 21.3 Ultrasound wavelength versus tissue thickness. To resolve the thickness of these structures, the ultrasound<br />

frequency must be much higher than listed in this table. Much lower-frequency ultrasound passes through with little<br />

interaction. For particles or cells, lower-frequency ultrasound is subject <strong>to</strong> Rayleigh scattering<br />

Tissue Property Dimension (mm) Ultrasound<br />

Speed (mm/µs) Frequency (MHz)<br />

Trachea Lumen diameter 25 0.32 0.013<br />

Aorta Lumen diameter 30 1.57 0.063<br />

Fat layer Subcutaneous 20 1.45 0.080<br />

Myocardium Thickness 10 1.6 0.16<br />

Skull Thickness 10 4 0.4<br />

Brain Cortex 3 1.5 0.5<br />

Artery Wall 0.8 1.6 2<br />

Trachea Wall 0.6 1.75 2.9<br />

Bone Cortex 1 4 4<br />

Eye Cornea 0.6 1.64 2.73<br />

Skin Dermis 0.3 1.73 5.76<br />

Fat Cell 0.1 1.45 14.5<br />

Brain Cell, large 0.1 1.5 15<br />

Skin Epidermis 0.05 1.73 35<br />

Erythrocyte Cell 0.007 1.57 225<br />

Bacteria Cell, large 0.005 1.5 300<br />

Brain Cell, small 0.004 1.5 375<br />

Notes:<br />

1. Trachea lumen: for phonation below 13 kHz, the trachea diameter is smaller than the wavelength so that the trachea acts like<br />

a waveguide, bounded by cartilage with acoustic velocity and impedance higher than the luminal air.<br />

2. Bone cortex and thin skull have thicknesses near the wavelength of transcranial ultrasound and a much higher ultrasound<br />

impedance, so the skull can act as an interference filter reflecting some wavelengths and passing others.<br />

3. As the upper limit of most medical ultrasound systems is 15 MHz, small animal research instruments image at frequencies as high<br />

as 70 MHz, high enough <strong>to</strong> resolve the epidermis and large brain cells, but not high enough <strong>to</strong> image most cells.<br />

number varies depending on the numeric aperture of<br />

the imaging system and on the acoustic contrast with<br />

the surrounding material. Small round structures such<br />

as tendons can be imaged using tricks, such as watching<br />

for motion, but most objects successfully imaged<br />

by ultrasound are larger. It is important <strong>to</strong> remember<br />

that it is possible <strong>to</strong> see an object that you cannot<br />

resolve. For instance, you are able see stars or<br />

lights at night, even though you cannot resolve closely<br />

spaced pairs of stars. When the signal from a target<br />

is strong, the target can be detected and located, even<br />

though a pair of targets cannot be resolved as two. If<br />

Doppler demodulation is used, rather than amplitude<br />

demodulation (used for B-mode), small vessels with<br />

Fig. 21.10 Near-field versus far-field difference in ultrasound<br />

image. This is an image taken with a diagnostic<br />

scanner using a 5 MHz ultrasound transducer (wavelength<br />

=0.3 mm) with a concavity radius of 16 mm and a transducer<br />

diameter of 6.4 mm. The computed transition zone<br />

is d 2 /4λ = 34 mm. The focus must be less than the 34 mm<br />

distance <strong>to</strong> the transition zone <strong>to</strong> be effective. With a fixedfocus<br />

fixed-aperture ultrasound transducer, the transition<br />

from the near field <strong>to</strong> the far field is marked by lateral<br />

spreading of the speckle in the far field. There is no effect<br />

on the range (depth) speckle dimension

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