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2011 – 2012Course DescriptionsBIOL 494 INDEPENDENT RESEARCH (1-3)Prerequisites: Consent of instructor andprogram approvalLaboratory and/or library research thatmay involve service learning in selectedareas of biology conducted under thedirection of a faculty member. All studentsare required to attend the BiologyProgram Senior Capstone Colloquium topresent their projects.Graded Credit/No CreditBIOL 497 DIRECTED STUDY (1-3)Prerequisites: Consent of instructor andprogram approvalReading and library research that mayinvolve service learning in selected areasof biology conducted under the directionof a faculty member. All students arerequired to attend the Biology ProgramSenior Capstone Colloquium to presenttheir projects.Graded Credit/No CreditBIOL 499 SENIOR CAPSTONEIN BIOLOGY (3)Three hours lecture per weekPrerequisite: Consent of instructorIntegration of previous coursework,knowledge and skills as they apply tospecific topics in Biology and the impactof biological science on society. Emphasiswill be placed on analysis of scientificliterature, problem solving and oral andwritten communication skills.BIOL 500 INTRODUCTION TOBIOPHARMACEUTICALPRODUCTION OPERATIONS (3)Three hours lecture per weekAn introduction to biopharmaceuticalproduction systems and processes. Topicsinclude manufacturing, unit operationsand supporting infrastructures, productdistribution, quality assurance and control,facility engineering and maintenance,utility operations, regulatory compliance,and laboratory support.BIOL 501 FUNDAMENTALS OF CELLULARAND MOLECULAR BIOLOGY (4)Four hours lecture per weekPrerequisites: BIOL 201 with a grade of Cor betterStudy of essential topics in cellular andmolecular biology. Topics include:structure and function of biologicalmacromolecules, membranes and cellularorganelles; cell signaling, synthesisof DNA, RNA and proteins; geneorganization, transcription and expression;basic molecular biology laboratorytechniques.BIOL 502 TECHNIQUES IN GENOMICS/PROTEOMICS (3)One hour lecture and six hours laboratoryper weekPrerequisites: BIOL 400, BIOL 401 orBIOL 501 or Consent of instructorProvides students with theoreticalfoundations and practial skills neededfor general bioinformatics, genomics,and proteomics analysis. Intensive labsessions, emphasize applied techniques.Field trips to various local biotechnologyfacilities will augment the training.BIOL 503 BIOTECHNOLOGY LAWAND REGULATION (3)Three hours lecture per weekIndividual and organizationalresponsibility in R&D and commercialaspects of biotechnology. Topics include:intellectual property, privacy, governmentand industrial regulation, liability, ethics,responsible conduct of research, andpolicy responses to societal concernsin the U.S. and abroad. Case studiesinvolving gene therapy, cloning, andbiomaterials in the medical and healthsector, and farming and crop modificationin the agricultural sector will be exploredin detail.BIOL 504 MOLECULAR CELL BIOLOGY (3)Three hours lecture per weekPrerequisites: BIOL 300 and BIOL 400 orBIOL 501 or Consent of instructorThis course will examine molecular andmechanistic aspects of cell biology.Topics include: cell biochemistry andbiosynthesis, cell signaling, regulation ofthe cell cycle and membrane trafficking.BIOL 505 MOLECULAR STRUCTURE (4)Three hours lecture and three hourslaboratory per weekPrerequisites: BIOL 504 or Consent ofinstructorExamines the structural biology ofproteins. Topics include general principlesof protein structure, the biochemicalfunction of proteins, the relationshipof protein structure to its function andexperimental approaches to determiningand predicting protein structure andfunction.BIOL 506 MOLECULAR EVOLUTION (4)Three hours lecture and three hourslaboratory per weekPrerequisites: BIOL 504 and Consent ofinstructorExamines evolutionary change at themolecular level. Topics include: Thedriving forces behind the evolutionaryprocess, the effects of the variousmolecular mechanisms on the structureof genes, proteins, and genomes, themethodology for dealing with moleculardata from an evolutionary perspectiveand the logic of molecular hypothesistesting.BIOL 507 PHARMACOGENOMICS ANDPHARMACOPROTEOMICS (3)Three hours lecture per weekPrerequisites: BINF 500, BIOL 504 orConsent of instructorStructural and functional genomics withan emphasis on how these fields operatein drug discovery and optimization.Topics include: genetics of the humanresponse to prophylactic and therapeuticagent, impact of genetic variation ontherapeutic efficacy, disease mechanisms,proteomics of genetic and communicabledisease, drug action and toxicity,structure encoding, lead discovery andoptimization, parallel synthesis, screeningvirtual libraries.BIOL 508 ADVANCED IMMUNOLOGY (4)Three hours lecture and three hourslaboratory per weekPrerequisites: BIOL 504 or Consent ofinstructorExamines cellular and molecular aspectsof the immune system. Topics include:molecular genetics and molecularstructure of immunoglobulin, T cellreceptor, and the MHC antigens; thefunctions and dysfunctions of thecomponents of the immune system;applications of immunologicaltechnologies in modern scientific researchand development.224 www.csuci.edu • California State University Channel Islands • 2011 - 2012 Catalog