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Exotic Animal Formulary5

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45 mg/kg q24h 103 nephrotoxic; maintain

hydration

Ticarcillin (Ticar, SmithKline-

Beecham)

50-100 mg/kg IM

q24h 103

50-100 mg/kg IM, IV

q24-48h 237

Most species/maintain hydration

Loggerhead sea turtles/PK

Tobramycin — Potentially nephrotoxic; maintain

hydration; potentiated by ß-

lactams

2.5 mg/kg IM q24-72h 79 Most species

10 mg/kg IM q24-48h 79 Chelonians/can be given q48h in

tortoises; fluid therapy

recommended

Trimethoprim/sulfadiazine or

sulfamethoxazole

— Maintain hydration; parenteral

form must be compounded

10-30 mg/kg PO q24h 117 Most species/maintain hydration

30 mg/kg IM

q24h×2 days, then

q48h 357

Tortoises/PD

Tylosin

5 mg/kg IM q24h×10-

60 days 79 Most species/mycoplasmosis

a

Because reptiles are ectothermic, pharmacokinetics of drugs are influenced by ambient temperature.

Antimicrobial therapy should be conducted at the upper end of the patient’s preferred (selected) optimum

temperature zone.

b

See Table 15-4 for antimicrobial combination therapies, some of which are commonly used in reptiles.

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