Exotic Animal Formulary5

of prohibited drugs, extra-label drugs, labeled drugs, and drugs needing a Veterinary Feed Directive prior
to choosing a drug and dose. Please refer to the Food Animal Residue Avoidance Databank at
www.farad.org and other sources listed in Table 6.25 for meat and egg withdrawal times.
Table 6-6
Nonsteroidal Antiinflammatory Agents Used in Backyard Poultry and Waterfowl. a,b
Agent Dosage Species/Comments
Acetaminophen
10 mg/kg IM
q24h×7 days 76
Chicken/no adverse clinical signs, normal serum
creatinine and uric acid, no gross or
histopathologic changes in kidneys observed
Aspirin
(acetylsalicylic
acid)
25 mg/kg IV 14,15 Chickens, ducks, turkeys
50 mg/kg PO 134a Chickens, turkeys/PK; mean residue time 7 hr
and 4.5 hr, respectively; 134a chickens/400 mg/kg
PO×14 days led to decreased weight gain and
ventricular ulceration 133,134a
50 mg/kg IV 134a Chickens, turkeys/PK; mean residue time 6 hr
and 3.3 hr, respectively
100-200 mg/kg IM 74 Chickens/partially reduced arthritic behaviors
after 1 hr
Dissolve five (5-grain)
aspirin tablets in
1 gal of water
(=324 mg/gal of
drinking water) 114
Poultry/offer solution free choice to obtain a
dosage rate of about 55 mg/kg body
weight/day 114
Carprofen 1 mg/kg SC 110 Chickens/improved locomotion for at least 90 min
post-injection
5-8 mg/kg PO q12h 173 Chickens
15-25 mg/kg SC 25 Chickens/PD; therapeutically effective treatment
of induced articular pain at 6 hr
30 mg/kg IM 74 Chickens/PD; arthritis painful behaviors reduced
1 hr post-treatment only with this high dose
40 mg/kg body
weight provided
in feed 38
Chickens/analgesia; dosage required to reach
similar mammalian therapeutic plasma
concentrations (8.3 µg/mL), but much lower
plasma concentrations (0.28 µg/mL) provided
some analgesia
Diclofenac — Chickens/toxic at dose of 2.5 mg/kg IM
q24h×7 days; severe clinical signs of renal
toxicity and high mortality with increased
serum creatinine and uric acid
577