Exotic Animal Formulary5

40 mg/kg PO, repeat
in 14 days 117
Milk and indigo snakes/amoebae;
flagellates
Emodepside
(1.98%)+praziquantel
(7.94%) (Profender,
Bayer)
1.12 mL/kg 265,337 Many species/PD; nematodes; cestodes;
aquatic turtles must be kept dry for
48 hr after application; appears to be
safe, but need more safety and efficacy
data
Fenbendazole — Drug of choice for nematodes; least toxic
of the benzimidazoles; may have an
antiprotozoan effect; overdose may
cause leukopenia, avoid in septicemic
patients 285
25-100 mg/kg PO
q14d for up to 4
treatments 38,169,196
All species/nematodes
100 mg/kg once 113 Tortoises/nematodes; shedding of ova
continues for 30 days
Fipronil (0.29%;
Frontline Spray,
Merial)
Imidocloprid and
moxidectin
(Advantage
multi/Advocate,
Bayer)
Wipe on then wash
off in 5 min q7-
10d prn 88,92
0.2 mg/kg topical
q14d×3
treatments 130
Most species/mites, ticks; beware of
reactions to alcohol carrier; needs
safety evaluation 117
Lizards/eliminated hookworms and
pinworms; needs safety and
pharmacokinetic evaluation
Ivermectin — Do not use in chelonians, 377 crocodilians,
indigo snakes, or skinks 38,117,199
0.2 mg/kg PO, SC,
IM, repeat in 14
days 93,117
5-10 mg/L water
topical spray q3-
Snakes (except indigos), lizards (except
skinks) 38 /nematodes (including
lungworms), 223 mites; can dilute with
propylene glycol for oral use; colored
animals may have skin discoloration at
injection site; rare adverse effects
reported in chameleons, possibly
associated with breakdown of
parasites; 16 do not use within 10 days
of diazepam or tiletamine/zolazepam;
rare death and occasional nervous
system signs, lethargy, or inappetence
have been reported; 199 used for
pentastomids in monitor lizards (with
dexamethasone 0.2 mg/kg q2d) 93
Snakes (except indigos), lizards (except
skinks)/mites; less effective than
139