Exotic Animal Formulary5

5-10 mg/kg SC, IM
administration 94 Chinchillas, not effective 94
20 mg/kg IP 65 Rats/anesthesia, 20-60 min; no
induction in 30% of animals
40 mg/kg IM, IP 84 Guinea pigs
80 mg/kg IP 108 Mice/surgical anesthesia for
~60 min
100 mg/kg SC, IP 48 Mice/anesthesia
Alfaxalone
(A)/butorphanol (B)
Alfaxalone
(A)/medetomidine
(Me)/butorphanol
(B)
Alfaxalone (A)/xylazine
(X)
Atipamezole (Antisedan,
Pfizer) a
(A) 5 mg/kg+(B) 0.5 mg/kg
IM 94
(A) 40-80 mg/kg+(Me)
0.3 mg/kg+(B) 5 mg/kg
SC 48
(A) 80 mg/kg+(X) 10 mg/kg
IP 108
5× the administered
medetomidine dose, or
10× the administered
dexmedetomidine dose
SC, IM 84
Chinchillas/short-term inconsistent
anesthesia (<20 min); significant
postanesthetic reduction in food
intake and fecal output 94
Mice/anesthesia; surgical anesthesia
for 35-85 min dependent on
alfaxalone dose; not effective
after IP administration
Mice/surgical anesthesia for
80±18 min
Dexmedetomidine/medetomidine
reversal
1 mg/kg SC 90 All species
Atropine 0.04-0.4 mg/kg SC, IM 90 Gerbils, hamsters, mice, rats/rats
possess serum atropinesterase
0.05-0.2 mg/kg SC, IM, IV 90 Chinchillas, guinea pigs
0.1-0.2 mg/kg SC, IM 84 Chinchillas, guinea pigs
Bupivacaine 0.5 mg/kg 3 Guinea pigs/nerve blocks
1 mg/kg+0.1 mg/kg morphine
(preservative free)
epidural 84
Limit volume to 0.33 mL/kg
1-2 mg/kg local nerve block 84 Guinea pig, rats
1.6 mg/kg epidural 84 Anesthesia to level of L4
2.3 mg/kg epidural 84 Anesthesia to level of
T11-13
Dexmedetomidine
(Dexdomitor, Orion)
— α 2 -agonist similar to medetomidine;
see ketamine for combination
Diazepam — See fentanyl/fluanisone and
671