Exotic Animal Formulary5

Cytosar 300 mg/m 2 SC×2 days (dilute 100 mg with 1 mL H 2 0)
4 Perform CBC c
5 Cytoxin 250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)
7 Methotrexate
Perform CBC c
0.8 mg/kg IM
8 Perform CBC c
9 Cytoxin 250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)
11 Cytosar 300 mg/m 2 SC×2 days (dilute 100 mg with 1 mL H 2 O)
Leukeran
1 tablet/animal PO or ½ tablet/animal PO×2 days
12 Perform CBC c
13 Cytoxin 250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)
15 Procarbazine 50 mg/m 2 PO q24h×14 days
16 Perform CBC c
17 Perform CBC c
18 Cytoxin 250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)
20 Cytosar 300 mg/m 2 SC×2 days (dilute 100 mg with 1 mL H 2 O)
Leukeran
1 tablet/animal PO or ½ tablet/animal PO×2 days
23 Cytoxin 250 mg/m 2 PO, SC (in 50 mL/kg of NaCl SC)
26 Procarbazine 50 mg/m 2 PO q24h×14 days
27 Perform CBC c and
chemistry panel
If not in remission, continue weeks 20-26 for 3 cycles
Protocol IV 4
Week Agent Dosage
3 days L-asparaginase 400 U/kg SC (premedicate with diphenhydramine)
1 Vincristine 0.12 mg/kg IV
Prednisone
Cyclophosphamide
1 mg/kg PO q24h continue throughout therapy
10 mg/kg PO
2 Vincristine 0.12 mg/kg IV
3 Vincristine 0.12 mg/kg IV
4 Vincristine 0.12 mg/kg IV
Cyclophosphamide
10 mg/kg PO
7, 10, 13, etc. Vincristine 0.12 mg/kg IV
Cyclophosphamide
10 mg/kg PO
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